Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche, 00185 Rome, Italy.
Int J Mol Sci. 2024 May 23;25(11):5657. doi: 10.3390/ijms25115657.
The generation of complex plant architectures depends on the interactions among different molecular regulatory networks that control the growth of cells within tissues, ultimately shaping the final morphological features of each structure. The regulatory networks underlying tissue growth and overall plant shapes are composed of intricate webs of transcriptional regulators which synergize or compete to regulate the expression of downstream targets. Transcriptional regulation is intimately linked to phytohormone networks as transcription factors (TFs) might act as effectors or regulators of hormone signaling pathways, further enhancing the capacity and flexibility of molecular networks in shaping plant architectures. Here, we focus on homeodomain-leucine zipper (HD-ZIP) proteins, a class of plant-specific transcriptional regulators, and review their molecular connections with hormonal networks in different developmental contexts. We discuss how HD-ZIP proteins emerge as key regulators of hormone action in plants and further highlight the fundamental role that HD-ZIP/hormone networks play in the control of the body plan and plant growth.
复杂的植物结构的产生取决于不同分子调控网络之间的相互作用，这些网络控制组织内细胞的生长，最终塑造每个结构的最终形态特征。组织生长和整体植物形状的调控网络由转录调控因子的复杂网络组成，这些因子协同或竞争以调节下游靶标的表达。转录调控与植物激素网络密切相关，因为转录因子（TFs）可能作为激素信号通路的效应物或调节剂发挥作用，进一步增强分子网络在塑造植物结构中的能力和灵活性。在这里，我们重点关注同源域亮氨酸拉链（HD-ZIP）蛋白，这是一类植物特异性转录调控因子，并综述了它们在不同发育背景下与激素网络的分子联系。我们讨论了 HD-ZIP 蛋白如何成为植物中激素作用的关键调节剂，并进一步强调了 HD-ZIP/激素网络在控制体节和植物生长中的基本作用。
