Sessa Giovanna, Morelli Giorgio, Sassi Massimiliano
Istituto di Biologia e Patologia Molecolari, Consiglio Nazionale delle Ricerche (IBPM-CNR), 00185 Rome, Italy.
Accademia Nazionale dei Lincei, 00165 Rome, Italy.
Plants (Basel). 2025 Aug 19;14(16):2574. doi: 10.3390/plants14162574.
The capacity of plants to generate new organs and tissues throughout their life cycle depends on the activity of the stem cells contained in meristematic tissues. Plant stem cells are organized in small, clustered populations referred to as stem cell niches. In addition to generating new undifferentiated cells, stem cell niches also provide the positional information that maintains stem cell self-renewal properties and controls the non-cell-autonomous differentiation of surrounding tissues. In this review, we aim to analyze and discuss the most recent literature describing the molecular mechanism controlling the activity and the organization of the stem cell niche in the root of the model plant (L.) Heynh. In particular, we will focus on the complex molecular regulatory networks that control the balance between stemness and differentiation in distal stem cells, as well as the maintenance of the mitotically inactive state of the quiescent center.
植物在其整个生命周期中生成新器官和组织的能力取决于分生组织中所含干细胞的活性。植物干细胞以小的、成簇的群体形式组织在一起，称为干细胞龛。除了产生新的未分化细胞外，干细胞龛还提供位置信息，维持干细胞的自我更新特性，并控制周围组织的非细胞自主性分化。在本综述中，我们旨在分析和讨论描述模式植物拟南芥根中控制干细胞龛活性和组织的分子机制的最新文献。特别是，我们将关注控制远端干细胞干性与分化之间平衡的复杂分子调控网络，以及静止中心有丝分裂非活性状态的维持。
