Rajovic Nina, Zagorac Slavisa, Cirkovic Andja, Matejic Bojana, Jeremic Danilo, Tasic Radica, Cumic Jelena, Masic Srdjan, Grupkovic Jovana, Mitrovic Vekoslav, Milic Natasa, Gluscevic Boris
Institute for Medical Statistics and Informatics, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.
Clinic for Orthopedic Surgery and Traumatology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
J Clin Med. 2024 May 24;13(11):3089. doi: 10.3390/jcm13113089.
: Due to their high frequency, common risk factors, and similar pathogenic mechanisms, musculoskeletal disorders (MSDs) are more likely to occur with other chronic illnesses, making them a "component disorder" of multimorbidity. Our objective was to assess the prevalence of multimorbidity and to identify the most common clusters of diagnosis within multimorbidity states, with the primary hypothesis that the most common clusters of multimorbidity are MSDs. : The current study employed data from a population-based 2019 European Health Interview Survey (EHIS). Multimorbidity was defined as a ≥2 diagnosis from the list of 17 chronic non-communicable diseases, and to define clusters, the statistical method of hierarchical cluster analysis (HCA) was performed. : Out of 13,178 respondents, multimorbidity was present among 4398 (33.4%). The HCA method yielded six multimorbidity clusters representing the most common diagnoses. The primary multimorbidity cluster, which was prevalent among both genders, age groups, incomes per capita, and statistical regions, consisted of three diagnoses: (1) lower spine deformity or other chronic back problem (back pain), (2) cervical deformity or other chronic problem with the cervical spine, and (3) osteoarthritis. : Given the influence of musculoskeletal disorders on multimorbidity, it is imperative to implement appropriate measures to assist patients in relieving the physical discomfort and pain they endure. Public health information, programs, and campaigns should be utilized to promote a healthy lifestyle. Policymakers should prioritize the prevention of MSDs by encouraging increased physical activity and a healthy diet, as well as focusing on improving functional abilities.
由于肌肉骨骼疾病（MSDs）发病率高、常见风险因素多且致病机制相似，它们更易与其他慢性疾病并发，成为多重疾病的“组成性疾病”。我们的目标是评估多重疾病的患病率，并确定多重疾病状态下最常见的诊断组合，主要假设是多重疾病最常见的组合是肌肉骨骼疾病。
本研究采用了基于人群的2019年欧洲健康访谈调查（EHIS）的数据。多重疾病被定义为在17种慢性非传染性疾病列表中诊断出≥2种疾病，为了确定组合，采用了层次聚类分析（HCA）的统计方法。
在13178名受访者中，4398人（33.4%）存在多重疾病。HCA方法产生了六个代表最常见诊断的多重疾病组合。主要的多重疾病组合在性别、年龄组、人均收入和统计区域中都很普遍，由三种诊断组成：（1）下脊柱畸形或其他慢性背部问题（背痛）；（2）颈椎畸形或颈椎其他慢性问题；（3）骨关节炎。
鉴于肌肉骨骼疾病对多重疾病的影响，必须采取适当措施帮助患者缓解他们所忍受的身体不适和疼痛。应利用公共卫生信息、项目和活动来促进健康的生活方式。政策制定者应优先预防肌肉骨骼疾病，鼓励增加体育活动和健康饮食，并注重提高功能能力。
