Blaszczyk Bartlomiej, Meira E Cruz Miguel, Waliszewska-Prosol Marta, Wieckiewicz Mieszko, Nowacki Dorian, Kanclerska Justyna, Lachowicz Gabriella, Wojakowska Anna, Michalek-Zrabkowska Monika, Przegralek Jakub, Smardz Joanna, Antosz Katarzyna, Mazur Grzegorz, Martynowicz Helena
Student Research Club No K133, Faculty of Medicine, Wroclaw Medical University, 213 Borowska St., 50-556 Wroclaw, Poland.
Sleep Unit, Centro Cardiovascular da Universidade de Lisboa, Department of Cardiology, Lisbon School of Medicine, 1649-028 Lisbon, Portugal.
J Clin Med. 2024 May 28;13(11):3154. doi: 10.3390/jcm13113154.
Comorbid insomnia and obstructive sleep apnea (COMISA) is not a well-identified sleep disorder, despite having a significant impact on health. This study investigates the relationship between sleep bruxism (SB) and sleep architecture in patients with COMISA, obstructive sleep apnea (OSA), and in those without any sleep disorders. : 119 patients were included in the study and divided into three groups: OSA, COMISA, and a control group. Polysomnographic (PSG) examination provided parameters related to sleep architecture, OSA, and characteristics of SB. : The bruxism episode index (BEI) and other SB parameters were not found to be statistically different between the three groups ( > 0.05). There was no statistical difference in measured sleep architecture between the COMISA and OSA groups ( > 0.05). In comparison to the control group, participants in the COMISA group were found to have an increased apnea-hypopnea index (AHI), oxygen desaturation index (ODI), respiratory disturbance index (RDI), all arousals (AA), and respiratory arousals (RA) ( < 0.05). Among COMISA patients, AA and RA were shown to have a positive linear correlation with the number of bradycardia events per hour (r = 0.49, r = 0.48, < 0.05). : SB does not occur in patients with COMISA more frequently than in patients with OSA or those without any sleep disorders. PSG parameters are not specific for COMISA; therefore, in order to differentiate this disorder from OSA alone, a comprehensive patient assessment has to be performed.
共病性失眠与阻塞性睡眠呼吸暂停（COMISA）尽管对健康有重大影响，但它并不是一种已明确的睡眠障碍。本研究调查了COMISA患者、阻塞性睡眠呼吸暂停（OSA）患者以及无任何睡眠障碍者的睡眠磨牙（SB）与睡眠结构之间的关系。119名患者纳入本研究并分为三组：OSA组、COMISA组和对照组。多导睡眠图（PSG）检查提供了与睡眠结构、OSA和SB特征相关的参数。三组之间的磨牙发作指数（BEI）和其他SB参数无统计学差异（P>0.05）。COMISA组和OSA组之间测量的睡眠结构无统计学差异（P>0.05）。与对照组相比，COMISA组参与者的呼吸暂停低通气指数（AHI）、氧饱和度下降指数（ODI）、呼吸紊乱指数（RDI）、总觉醒次数（AA）和呼吸觉醒次数（RA）均增加（P<0.05）。在COMISA患者中，AA和RA与每小时心动过缓事件的数量呈正线性相关（r=0.49，r=0.48，P<0.05）。COMISA患者中SB的发生率并不比OSA患者或无任何睡眠障碍者更高。PSG参数对COMISA不具有特异性；因此，为了仅将这种疾病与OSA区分开来，必须对患者进行全面评估。
