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心脏结节病中的心律失常:管理与预后意义

Arrhythmias in Cardiac Sarcoidosis: Management and Prognostic Implications.

作者信息

Arunachalam Karikalan Suganya, Yusuf Ali, El Masry Hicham

机构信息

Department of Cardiovascular Medicine, Mayo Clinic, Phoenix, AZ 85054, USA.

Department of Internal Medicine, Texas Tech University Health Sciences, Amarillo, TX 79430, USA.

出版信息

J Clin Med. 2024 May 28;13(11):3165. doi: 10.3390/jcm13113165.

Abstract

Cardiac sarcoidosis (CS) is characterized by various arrhythmic manifestations ranging from catastrophic sudden cardiac death secondary to ventricular arrhythmia, severe conduction disease, sinus node dysfunction, and atrial fibrillation. The management of CS is complex and includes not only addressing the arrhythmia but also controlling the myocardial inflammation resultant from the autoimmune reaction. Arrhythmic manifestations of CS carry significant prognostic implications and invariably affect long-term survival in these patients. In this review, we focus on management of arrhythmic manifestation of cardiac sarcoidosis as well as risk stratification for sudden cardiac death in these patients.

摘要

心脏结节病(CS)的特征是出现各种心律失常表现,从继发于室性心律失常、严重传导疾病、窦房结功能障碍和心房颤动的灾难性心脏性猝死。CS的管理很复杂,不仅包括处理心律失常,还包括控制自身免疫反应导致的心肌炎症。CS的心律失常表现具有重要的预后意义,并始终影响这些患者的长期生存。在本综述中,我们重点关注心脏结节病心律失常表现的管理以及这些患者心脏性猝死的风险分层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f22/11172558/2e07b87589c8/jcm-13-03165-g001.jpg

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