Jaber Mohamed, Prasad Prathibha, Akeil Mohammad, Moufti Abdulrahman, Al-Sammarraie Almustafa, Charaf Eddin Chuaeib
College of Dentistry, Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman P.O. Box 346, United Arab Emirates.
Department of Oral Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 600077, India.
J Clin Med. 2024 Jun 5;13(11):3341. doi: 10.3390/jcm13113341.
: This umbrella review of systematic reviews aims to summarize the available data regarding both success and survival rates of tooth autotransplantation, in addition to analyzing the risk factors that are connected to those rates. This umbrella review was performed according to the evaluation of various meta-analyses and systematic reviews following AMSTAR2 guidelines. A systematic search of literature on PubMed, Scopus, MEDLINE, EMBASE, and the Cochrane Database. Six systematic reviews were included. Explicit inclusion and exclusion criteria were applied. It is registered in PROSPERO under the registration number (CRD-42023415623). The studies reviewed were written from 2014 to 2018, which extracted the information from various studies spanning from 1968 to 2014. According to the selected studies regarding autotransplanted teeth in humans, they showed the following: A survival rate overall of 87.39% and a success rate overall of 90.29%. These factors were the most common in relation to the success of the autotransplanted teeth: age, gender, and stage of root development. On the other hand, common unfavorable results linked to the transplanted teeth in these studies were failure, ankylosis, and internal root resorption, followed by extraction and hypermobility. The wide body of evidence gathered illustrates that autotransplantation is an operation that dispenses high rates of survival and success. Furthermore, risk factors like root development stage, recipient site, and donor tooth type established a remarkable association with the negative outcomes of the procedure. For successful tooth autotransplantation, patient selection is crucial. Younger patients and those with donor teeth at an optimal stage of root development typically experience better outcomes. Preoperative planning should include comprehensive evaluations and advanced imaging techniques to accurately assess both the donor tooth and the recipient site. Nonetheless, on account of heterogeneity and the quality of the studies included in this investigation, caution should be taken when interpreting the mentioned results.
本系统评价的伞状综述旨在总结关于牙齿自体移植成功率和存活率的现有数据,并分析与这些比率相关的风险因素。本伞状综述是根据遵循AMSTAR2指南对各种荟萃分析和系统评价进行评估后进行的。对PubMed、Scopus、MEDLINE、EMBASE和Cochrane数据库进行了系统的文献检索。纳入了六项系统评价。应用了明确的纳入和排除标准。它已在PROSPERO注册,注册号为(CRD-42023415623)。所审查的研究发表于2014年至2018年,其从1968年至2014年的各种研究中提取信息。根据所选的关于人类自体移植牙齿的研究,结果如下:总体存活率为87.39%,总体成功率为90.29%。与自体移植牙齿成功相关的这些因素最为常见:年龄、性别和牙根发育阶段。另一方面,这些研究中与移植牙齿相关的常见不良结果是失败、牙根粘连和牙根内吸收,其次是拔牙和牙齿松动。收集的大量证据表明,自体移植是一种具有高存活率和成功率的手术。此外,诸如牙根发育阶段、受植部位和供体牙类型等风险因素与该手术的负面结果有着显著关联。对于成功的牙齿自体移植,患者选择至关重要。年轻患者和牙根发育处于最佳阶段的供体牙患者通常预后更好。术前规划应包括全面评估和先进的成像技术,以准确评估供体牙和受植部位。尽管如此,由于本研究中纳入研究的异质性和质量,在解释上述结果时应谨慎。