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子宫动静脉畸形:诊断与治疗挑战

Uterine Arteriovenous Malformation: Diagnostic and Therapeutic Challenges.

作者信息

Clavero Bertomeu Luisa, Castro Portillo Laura, Fernández-Conde de Paz Cristina

机构信息

Department of Obstetrics and Gynecology, Valme University Hospital, 41014 Sevilla, Spain.

出版信息

Diagnostics (Basel). 2024 May 23;14(11):1084. doi: 10.3390/diagnostics14111084.

Abstract

Uterine arteriovenous malformations are a rare cause of puerperal haemorrhage, but their incidence is increasing due to both improved diagnosis and the more frequent use of uterine surgery in recent years. The use of ultrasound, both B-mode and Doppler, is recommended for diagnosis and follow-up, as it has been shown to be the simplest and most cost-effective method. Endometrial thickening associated with an anechoic and vascular intramiometrial structure is very useful for diagnosis and can help to exclude other causes of dysfunctional bleeding. Pulsed Doppler shows low-resistance vessels and high pulsatility indices with a high peak systolic velocity (PSV). In a healthy myometrium, the vessels have a peak systolic velocity of 9-40 cm/s and a resistance index between 0.6 and 0.8, whereas in the case of AVMs, the systolic and diastolic velocities are 4-6 times higher (PSV 25-110 cm/s with a mean of 60 cm/s and a resistance index of 0.27-0.75 with a mean of 0.41). For treatment, we must individualise each case, taking into account haemodynamic stability, the patient's reproductive wishes, and the severity of the AVM as assessed by its size and PSV.

摘要

子宫动静脉畸形是产后出血的罕见原因,但由于诊断技术的改进以及近年来子宫手术的更频繁应用,其发病率正在上升。推荐使用B超和多普勒超声进行诊断及随访,因为这已被证明是最简单且最具成本效益的方法。与肌层内无回声且有血管的结构相关的子宫内膜增厚对诊断非常有用,并且有助于排除其他功能性出血的原因。脉冲多普勒显示低阻力血管和高搏动指数,收缩期峰值速度(PSV)较高。在健康的肌层中,血管的收缩期峰值速度为9 - 40厘米/秒,阻力指数在0.6至0.8之间,而在动静脉畸形的情况下,收缩期和舒张期速度要高4 - 6倍(PSV为25 - 110厘米/秒,平均为60厘米/秒,阻力指数为0.27 - 0.75,平均为0.41)。对于治疗,我们必须根据每例情况进行个体化处理,要考虑到血流动力学稳定性、患者的生育意愿以及根据动静脉畸形的大小和PSV评估的严重程度。

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