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临床疑似恶性肿瘤的子宫动静脉畸形罕见病例:给病理学家的重要提示

Rare occurrence of uterine arteriovenous malformation clinically mimicking a malignant growth: A critical reminder for pathologists.

作者信息

Lollie Trang K, Raman Steven S, Qorbani Amir, Farzaneh Ted, Moatamed Neda A

机构信息

University of California (UCLA), David Geffen School of Medicine, Department of Pathology and Laboratory Medicine. Los Angeles, CA, USA.

University of California (UCLA), David Geffen School of Medicine, Department of Radiological Sciences. Los Angeles, CA, USA.

出版信息

Autops Case Rep. 2020 Jun 5;10(3):e2020144. doi: 10.4322/acr.2020.144.

Abstract

Arteriovenous malformation (AVM) is a rare lesion in the uterus, which can lead to abnormal uterine bleeding. While AVM has been described in other organs in the literature, there is a paucity of pathology reports of the AVM in uterus. On gross examination, the uterus was markedly enlarged and partly distorted with a pedunculated solid mass, which on the cut surface showed multiple well-circumscribed hemorrhagic cysts ranging from 0.1 to 4.0 cm in size. Microscopically, they were malformed dilated vascular structures containing organized thrombi. We present this case of uterine AVM with gross and microscopic findings, which can serve as a crucial reminder for pathologists to keep in the differential diagnoses as a potential cause of abnormal uterine bleeding.

摘要

动静脉畸形(AVM)是子宫内一种罕见的病变,可导致子宫异常出血。虽然文献中已报道AVM存在于其他器官,但子宫AVM的病理学报告却很少。大体检查时,子宫明显增大,部分变形,有一个带蒂的实性肿块,切面可见多个边界清晰的出血性囊肿,大小从0.1厘米到4.0厘米不等。显微镜下,它们是畸形扩张的血管结构,含有机化血栓。我们展示了这例子宫AVM的大体和显微镜下表现,这可作为一个重要提示,提醒病理学家在鉴别诊断时将其作为子宫异常出血的潜在原因之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a2a/7703198/b975d098d91f/autopsy-10-3-e2020144-gf01.jpg

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