Wysocki Andrzej, Fułek Michał, Macek Piotr, Michałek-Zrąbkowska Monika, Kraik Krzysztof, Poręba Małgorzata, Fułek Katarzyna, Martynowicz Helena, Mazur Grzegorz, Gać Paweł, Poręba Rafał
Centre for Diagnostic Imaging, 4th Military Hospital, 50-981 Wroclaw, Poland.
Department of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 213 Borowska St., 50-556 Wroclaw, Poland.
Diagnostics (Basel). 2024 May 25;14(11):1101. doi: 10.3390/diagnostics14111101.
The aim of the study was to assess the relationship between the presence of atherosclerotic lesions in the carotid arteries detected by ultrasound and the occurrence of atherosclerosis in the coronary arteries determined by computed tomography (CT) in patients with arterial hypertension (HTA). A total of 83 patients with HTA were qualified for the study (age: 71.3 ± 8.5 years). All subjects underwent carotid arteries ultrasound and coronary arteries CT. The carotid plaque score was assessed using ultrasound. The studied group was divided into two subgroups: a subgroup with the carotid plaque score ≤ 1 (A) and a subgroup with carotid plaque score ≥2 (B). Coronary arteries CT assessed coronary artery calcium score (CACS) and degree of coronary stenosis based on CAD-RADS. In subgroup B, a significantly higher CACS (411.3 ± 70.1 vs. 93.5 ± 31.8) and significantly higher grade in the CAD-RADS classification were demonstrated than in subgroup A (CAD-RADS ≥ 3: 21.8 vs. 6.0%). The regression analysis showed that carotid plaque score and age are independent risk factors for the severity of atherosclerotic lesions in the coronary arteries. In summary, ultrasound assessment of the carotid plaque score in patients with HTA could be considered as surrogate indicator of the risk and severity of atherosclerotic changes in the coronary arteries, but further studies are necessary to corroborate these results.
本研究的目的是评估动脉高血压（HTA）患者中，通过超声检测到的颈动脉粥样硬化病变的存在与通过计算机断层扫描（CT）确定的冠状动脉粥样硬化的发生之间的关系。共有83例HTA患者入选本研究（年龄：71.3±8.5岁）。所有受试者均接受了颈动脉超声和冠状动脉CT检查。使用超声评估颈动脉斑块评分。研究组分为两个亚组：颈动脉斑块评分≤1的亚组（A）和颈动脉斑块评分≥2的亚组（B）。冠状动脉CT根据CAD-RADS评估冠状动脉钙化评分（CACS）和冠状动脉狭窄程度。在亚组B中，与亚组A相比，CACS显著更高（411.3±70.1 vs. 93.5±31.8），且CAD-RADS分类中的分级显著更高（CAD-RADS≥3：21.8% vs. 6.0%）。回归分析表明，颈动脉斑块评分和年龄是冠状动脉粥样硬化病变严重程度的独立危险因素。总之，对HTA患者的颈动脉斑块评分进行超声评估可被视为冠状动脉粥样硬化改变风险和严重程度的替代指标，但需要进一步研究来证实这些结果。
