Kosmidis Christoforos, Boulogeorgou Kassiani, Roulia Panagiota, Dagher Marios, Anthimidis Georgios, Petrakis Georgios, Koulouris Charilaos, Mantalovas Stylianos, Laskou Styliani, Magra Vasiliki, Karakousis Vasileios Alexandros, Sevva Christina, Paschou Eleni, Stergios Vasileios, Kosmidis Stylianos, Mystakidou Chrysi Maria, Theodorou Vasiliki, Katsios Nikolaos Iason, Koletsa Triantafyllia, Sapalidis Konstantinos, Kesisoglou Isaak
3rd Surgical Department, University General Hospital of Thessaloniki "AHEPA", Aristotle University of Thessaloniki, 1st St. Kiriakidi Street, 54621 Thessaloniki, Greece.
Department of Pathology, School of Medicine, Aristotle University of Thessaloniki, 54621 Thessaloniki, Greece.
Diagnostics (Basel). 2024 May 29;14(11):1133. doi: 10.3390/diagnostics14111133.
Breast cancer is the most common type of cancer of the female gender. A rare subtype of breast cancer is the invasive breast carcinoma (IBC) with neuroendocrine (NE) differentiation. Its incident is believed to be 0.1% to 5% of all breast cancers. We report a rare case of a 66-year old woman who presented with an isolated nodule of the left breast. The patient underwent modified radical mastectomy. Pathology revealed invasive breast carcinoma with neuroendocrine differentiation. Invasive breast carcinoma is an extremely rare group of neoplasms, the exact frequency of which cannot be determined with current data. Therefore, it is necessary for future studies to focus on the pathophysiology of this subtype of breast cancer and on the potential therapeutic approaches.
乳腺癌是女性中最常见的癌症类型。一种罕见的乳腺癌亚型是具有神经内分泌（NE）分化的浸润性乳腺癌（IBC）。据信其发病率占所有乳腺癌的0.1%至5%。我们报告一例罕见病例，一名66岁女性，以左乳孤立性结节就诊。患者接受了改良根治性乳房切除术。病理显示为具有神经内分泌分化的浸润性乳腺癌。浸润性乳腺癌是一组极其罕见的肿瘤，目前的数据尚无法确定其确切发病率。因此，未来的研究有必要聚焦于这种乳腺癌亚型的病理生理学以及潜在的治疗方法。
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