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[用氰基丙烯酸丁酯对脑动静脉畸形进行术中栓塞治疗(18例)]

[Peroperative embolization of cerebral arteriovenous malformations with butylcyanoacrylate (18 cases)].

作者信息

Deruty R, Lapras C, Pierluca P, Patet J D, Pialat J, Bascoulergues Y, Garcia C

出版信息

Neurochirurgie. 1985;31(1):21-9.

PMID:3889682
Abstract

18 cases of cerebral Arterio-Venous malformations (AVM) are reported, treated by direct intra-operative embolisation. A 50% mixture of Butyl-2-Cyanoacrylate and Mono-Iodo-Stearate of Ethyl was used. The clinical history of the patients was a long history of seizures in 8 cases a sub-arachnoid or intra-cerebral hemorrhage in 9 cases, and a transient motor deficit in 1 case. The AVM site was supra-tentorial in 16 cases, and infra-tentorial in 2 cases. The AVM size was large with numerous feeders in 13 cases, and limited with a few feeders in 5 cases. Technically, after catheterisation of a cortical feeder, an intra-operative angiogram was performed (except for the first 6 cases) then the polymerizing mixture was pushed inside the feeder (from 1 cc to 3 cc routinely, depending of the AVM size; exceptionally 7 cc and 11 cc were used). In the immediate postoperative course, 1 patient died (case with the 11 cc embolization), 3 patients had a serious postoperative hemorrhage, 4 patients presented with a transient postoperative deficit, and in 10 patients the postoperative course was uneventful. The long term results are: 1 postoperative death, 1 death after recurrence of intra-cerebral hemorrhage (3 years postoperatively), 1 hemiplegia, 15 patients without long lasting complication. The embolization was performed as unique treatment in 14 cases, and was followed with the AVM removal in 4 cases (immediately in 1 case, delayed in 1 case, late after recurrence of intra-cerebral hemorrhage in 2 cases, respectively after 3 years and 2 years).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

报告了18例脑动静脉畸形(AVM)患者,采用术中直接栓塞治疗。使用了丁基-2-氰基丙烯酸酯和乙基单碘硬脂酸酯的50%混合物。患者的临床病史包括:8例有长期癫痫病史,9例有蛛网膜下腔或脑内出血病史,1例有短暂运动功能障碍。AVM部位幕上16例,幕下2例。AVM大小方面,13例大且有众多供血支,5例小且供血支少。技术上,在对皮质供血支进行插管后(前6例除外),进行术中血管造影,然后将聚合混合物注入供血支(通常根据AVM大小注入1至3毫升,特殊情况下使用7毫升和11毫升)。术后即刻,1例患者死亡(栓塞11毫升的病例),3例患者发生严重术后出血,4例患者出现短暂术后功能障碍,10例患者术后过程顺利。长期结果为:1例术后死亡,1例脑内出血复发后死亡(术后3年),1例偏瘫,15例无长期并发症。14例栓塞作为唯一治疗方法,4例栓塞后行AVM切除(1例立即切除,1例延迟切除,2例脑内出血复发后晚期切除,分别在3年和2年后)。(摘要截选至250字)

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