限时进食结合运动对身体成分和代谢健康的影响：系统评价和荟萃分析。

The Effect of Time-Restricted Eating Combined with Exercise on Body Composition and Metabolic Health: A Systematic Review and Meta-Analysis.

机构信息

Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China.

Department of Sports Science and Physical Education, The Chinese University of Hong Kong, Hong Kong, China; Dr. Stephen Hui Research Centre for Physical Recreation and Wellness, Hong Kong Baptist University, Hong Kong, China.

出版信息

Adv Nutr. 2024 Aug;15(8):100262. doi: 10.1016/j.advnut.2024.100262. Epub 2024 Jun 17.

DOI:10.1016/j.advnut.2024.100262

PMID:38897385

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11301358/

Abstract

BACKGROUND

Time-restricted eating (TRE) is increasingly popular, but its benefits in combination with exercise still need to be determined.

OBJECTIVES

This systematic review and meta-analysis aimed to evaluate the efficacy of TRE combined with exercise compared with control diet with exercise in improving the body composition and metabolic health of adults.

METHODS

Five electronic databases were searched for relevant studies. Randomized controlled trials (RCTs) examining the effect of TRE combined with exercise on body composition and metabolic health in adults were included. All results in the meta-analysis are reported as mean difference (MD) with 95% confidence interval (CI). Study quality was assessed using the revised Cochrane Risk of Bias Tool and Grading of Recommendations Assessment, Development, and Evaluation assessment.

RESULTS

In total, 19 RCTs comprising 568 participants were included in this systematic review and meta-analysis. TRE combined with exercise likely reduced the participants' body mass (MD: -1.86 kg; 95% CI: -2.75, -0.97 kg) and fat mass (MD: -1.52 kg; 95% CI: -2.07, -0.97 kg) when compared with the control diet with exercise. In terms of metabolic health, the TRE combined with exercise group likely reduced triglycerides (MD: -13.38 mg/dL, 95% CI: -21.22, -5.54 mg/dL) and may result in a reduction in low-density lipoprotein (MD: -8.52 mg/dL; 95% CI: -11.72, -5.33 mg/dL) and a large reduction in leptin (MD: -0.67 ng/mL; 95% CI: -1.02, -0.33 ng/mL). However, TRE plus exercise exhibited no additional benefit on the glucose profile, including fasting glucose and insulin, and other lipid profiles, including total cholesterol and high-density lipoprotein concentrations, compared with the control group.

CONCLUSIONS

Combining TRE with exercise may be more effective in reducing body weight and fat mass and improving lipid profile than control diet with exercise. Implementing this approach may benefit individuals aiming to achieve weight loss and enhance their metabolic well-being. This study was registered in PROSPERO as CRD42022353834.

摘要

背景

限时进食（TRE）越来越受欢迎，但它与运动相结合的益处仍需确定。

目的

本系统评价和荟萃分析旨在评估 TRE 联合运动与对照饮食联合运动相比，改善成年人身体成分和代谢健康的效果。

方法

检索了五个电子数据库，以寻找有关 TRE 联合运动对成年人身体成分和代谢健康影响的研究。纳入了研究 TRE 联合运动对成年人身体成分和代谢健康影响的随机对照试验（RCT）。荟萃分析中的所有结果均以均值差（MD）和 95%置信区间（CI）表示。使用修订后的 Cochrane 偏倚风险工具和 Grading of Recommendations Assessment, Development, and Evaluation 评估对研究质量进行评估。

结果

本系统评价和荟萃分析共纳入 19 项 RCT，共 568 名参与者。与对照饮食联合运动相比，TRE 联合运动可能降低参与者的体重（MD：-1.86kg；95%CI：-2.75，-0.97kg）和脂肪量（MD：-1.52kg；95%CI：-2.07，-0.97kg）。在代谢健康方面，TRE 联合运动组可能降低甘油三酯（MD：-13.38mg/dL；95%CI：-21.22，-5.54mg/dL），并可能降低低密度脂蛋白（MD：-8.52mg/dL；95%CI：-11.72，-5.33mg/dL）和瘦素（MD：-0.67ng/mL；95%CI：-1.02，-0.33ng/mL）。然而，与对照组相比，TRE 加运动在血糖谱（包括空腹血糖和胰岛素）和其他脂质谱（包括总胆固醇和高密度脂蛋白浓度）方面没有显示出额外的益处。