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急性髓性白血病异基因造血干细胞移植后嗜酸性食管炎的组织学缓解

Histological Remission of Eosinophilic Esophagitis Following Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myelogenous Leukemia.

作者信息

Méndez Gabriela, Griggs Theodor, Ludi Daniel, Yazici Cemal, Yeon Su Yeon

机构信息

Internal Medicine, University of Illinois at Chicago, Chicago, USA.

Gastroenterology and Hepatology, University of Illinois at Chicago, Chicago, USA.

出版信息

Cureus. 2024 May 20;16(5):e60687. doi: 10.7759/cureus.60687. eCollection 2024 May.

DOI:10.7759/cureus.60687
PMID:38899237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11186572/
Abstract

Eosinophilic esophagitis (EoE) is an immune/antigen-mediated disease with an increasing incidence over the last decade. Clinicopathological remission can be achieved through different treatment options but often requires chronic therapy. To our knowledge, this is the first report of EoE wherein the patient (a 54-year-old man) achieved histological remission after allogeneic hematopoietic stem cell transplantation (HSCT) for acute myelogenous leukemia. Overall, despite the success of EoE treatment in this case, further studies are needed to establish allogeneic HSCT as a curative option for EoE.

摘要

嗜酸性粒细胞性食管炎（EoE）是一种免疫/抗原介导的疾病，在过去十年中发病率不断上升。通过不同的治疗方案可以实现临床病理缓解，但通常需要长期治疗。据我们所知，这是首例关于EoE的报告，该患者（一名54岁男性）在接受急性髓性白血病的异基因造血干细胞移植（HSCT）后实现了组织学缓解。总体而言，尽管该病例中EoE治疗取得了成功，但仍需要进一步研究以确立异基因HSCT作为EoE的一种治愈性选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/c0be5a4a558d/cureus-0016-00000060687-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/c354e123bdc8/cureus-0016-00000060687-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/93411281fb59/cureus-0016-00000060687-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/c0be5a4a558d/cureus-0016-00000060687-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/c354e123bdc8/cureus-0016-00000060687-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/93411281fb59/cureus-0016-00000060687-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df2a/11186572/c0be5a4a558d/cureus-0016-00000060687-i03.jpg

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Dupilumab in Adults and Adolescents with Eosinophilic Esophagitis.度普利尤单抗在成人和青少年嗜酸性食管炎中的应用。
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