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经颅多普勒超声检查显示眼动脉血流反向与眼灌注压降低相关。

Decreased Ocular Perfusion Pressure Associated With Reverse Ophthalmic Artery Flow on Transcranial Doppler Ultrasonography.

作者信息

Murillo Brian A, Cheng Anny M, Tsai Joby, Gupta Shailesh K

机构信息

Ophthalmology, New York Medical College, Valhalla, USA.

Ophthalmology, Broward Health, Fort Lauderdale, USA.

出版信息

Cureus. 2024 May 20;16(5):e60706. doi: 10.7759/cureus.60706. eCollection 2024 May.

DOI:10.7759/cureus.60706
PMID:38899251
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11186674/
Abstract

Innovative applications of clinical ocular diagnostic tools are emerging to help identify systemic disorders that extend beyond ocular diseases. Ophthalmodynamometry (ODM) is a screening tool that non-invasively determines mean central retinal artery pressure (MCRAP) and ocular perfusion pressure (OPP). Decreased OPP and MCRAP on Falck Medical Multifunctional Device (FMD, Falck Medical, Inc., Mystic, CT), along with reverse ophthalmic artery flow (ROAF) on transcranial Doppler ultrasonography (TCD), indicate increased collateral brain perfusion and possible stenosis of the ophthalmic artery or internal carotid artery (ICA). In this case report, we describe the case of a 78-year-old female with ROAF, reduced MCRAP, and OPP in the right eye, confirmed by carotid duplex of 50-79% right ICA stenosis. Early application of ODM and TCD allowed for prompt diagnosis and management with a vascular specialist.

摘要

临床眼科诊断工具的创新应用正在兴起,以帮助识别超出眼部疾病范围的全身性疾病。眼血流动力学测量法(ODM)是一种非侵入性测定视网膜中央动脉平均压(MCRAP)和眼灌注压(OPP)的筛查工具。Falck医疗多功能设备(FMD,Falck医疗公司,康涅狄格州神秘市)上的OPP和MCRAP降低,以及经颅多普勒超声检查(TCD)上的眼动脉反向血流(ROAF),表明侧支脑灌注增加以及眼动脉或颈内动脉(ICA)可能存在狭窄。在本病例报告中,我们描述了一名78岁女性的病例,其右眼存在ROAF、MCRAP降低和OPP降低,经颈动脉双功超声检查证实右侧ICA狭窄50 - 79%。早期应用ODM和TCD使得能够及时由血管专科医生进行诊断和管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7435/11186674/4f118ef6d9be/cureus-0016-00000060706-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7435/11186674/4f118ef6d9be/cureus-0016-00000060706-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7435/11186674/4f118ef6d9be/cureus-0016-00000060706-i01.jpg

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本文引用的文献

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Papillomacular bundle defect (PMBD) in glaucoma patients with high myopia: frequency and risk factors.青光眼高度近视患者的乳头黄斑束纤维缺损(PMBD):频率和危险因素。
Sci Rep. 2023 Dec 11;13(1):21958. doi: 10.1038/s41598-023-48687-0.
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Role of Doppler Ultrasound Analysis of Blood Flow Through the Ophthalmic and Intracranial Arteries in Predicting Neurologic Symptoms During Carotid Endarterectomy.经颅多普勒超声分析眼动脉和颅内动脉血流在预测颈动脉内膜切除术期间神经症状中的作用。
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Carotid artery stenosis, an underestimated cause of stroke recurrence in patients with ischaemic monocular visual loss.
颈动脉狭窄,缺血性单眼视力丧失患者中风复发的一个被低估的原因。
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Reversal of ophthalmic artery flow as a predictor of intracranial hemodynamic compromise: implication for prognosis of severe carotid stenosis.眼动脉血流逆转作为颅内血流动力学受损的预测指标:对严重颈动脉狭窄预后的影响。
Eur J Neurol. 2013 Mar;20(3):564-570. doi: 10.1111/ene.12038. Epub 2012 Dec 24.
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Reproducibility of ophthalmodynamometric measurements of central retinal artery and vein collapse pressure.视网膜中央动脉和静脉压陷压力的眼压测量法的可重复性
Br J Ophthalmol. 2003 May;87(5):577-9. doi: 10.1136/bjo.87.5.577.
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Ophthalmic artery flow direction on color flow duplex imaging is highly specific for severe carotid stenosis.彩色血流双功成像上眼动脉的血流方向对严重颈动脉狭窄具有高度特异性。
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Stroke. 1993 Aug;24(8):1196-203. doi: 10.1161/01.str.24.8.1196.
9
Ophthalmodynamometry in internal carotid artery occlusion.
Stroke. 1976 Nov-Dec;7(6):564-6. doi: 10.1161/01.str.7.6.564.