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阿司匹林诱发的巨大自发性舌下血肿。

Aspirin-Induced Massive Spontaneous Sublingual Hematoma.

作者信息

Mishra Utkal P, Behera Ganakalyan, Handa Prince, Singh Rohit, Nawas Fasin

机构信息

Otolaryngology - Head and Neck Surgery, All India Institute of Medical Sciences, Bhopal, IND.

出版信息

Cureus. 2024 May 20;16(5):e60684. doi: 10.7759/cureus.60684. eCollection 2024 May.

DOI:10.7759/cureus.60684
PMID:38899276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11186571/
Abstract

Sublingual hematoma, a rare but potentially life-threatening condition, can arise spontaneously or secondary to various triggers, including trauma, dental procedures, or anticoagulant therapy. We present a case of massive spontaneous sublingual hematoma in a 45-year-old woman receiving aspirin therapy for rheumatic heart disease. Despite the absence of trauma or procedural triggers, the patient presented with bleeding from the floor of the mouth and significant submental swelling, prompting urgent intervention to secure the airway and manage coagulopathy. Conservative measures, including discontinuation of aspirin and intravenous vitamin K administration, led to gradual hematoma resolution and favorable patient outcomes. This case highlights the importance of prompt recognition and early management of sublingual hematoma, particularly in the context of aspirin therapy-induced coagulopathy.

摘要

舌下血肿是一种罕见但可能危及生命的病症,可自发出现或继发于各种诱因,包括创伤、牙科手术或抗凝治疗。我们报告一例45岁患有风湿性心脏病且正在接受阿司匹林治疗的女性发生大规模自发性舌下血肿的病例。尽管没有创伤或手术诱因,但该患者出现了口腔底部出血和明显的颏下肿胀,促使进行紧急干预以确保气道安全并处理凝血功能障碍。包括停用阿司匹林和静脉注射维生素K在内的保守措施使血肿逐渐消退,患者预后良好。该病例强调了及时识别和早期处理舌下血肿的重要性,尤其是在阿司匹林治疗引起凝血功能障碍的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8072/11186571/4900cbfde3c2/cureus-0016-00000060684-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8072/11186571/e573cc6533b1/cureus-0016-00000060684-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8072/11186571/4900cbfde3c2/cureus-0016-00000060684-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8072/11186571/e573cc6533b1/cureus-0016-00000060684-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8072/11186571/4900cbfde3c2/cureus-0016-00000060684-i02.jpg

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引用本文的文献

1
Sublingual hematoma as a rare complication of warfarin therapy in a patient with rheumatic heart disease: a case report.风湿性心脏病患者华法林治疗罕见并发症——舌下血肿:一例报告
Ann Med Surg (Lond). 2024 Sep 25;86(11):6828-6831. doi: 10.1097/MS9.0000000000002603. eCollection 2024 Nov.

本文引用的文献

1
Management of Spontaneous Neck Hematoma in Patients  on Anticoagulant Therapy: Our Experience from a Tertiary Care Center.抗凝治疗患者自发性颈部血肿的管理:来自三级医疗中心的经验
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):6362-6366. doi: 10.1007/s12070-021-02990-2. Epub 2022 Apr 13.
2
Association of Aspirin Use for Primary Prevention With Cardiovascular Events and Bleeding Events: A Systematic Review and Meta-analysis.阿司匹林用于一级预防与心血管事件及出血事件的相关性:系统评价和荟萃分析。
JAMA. 2019 Jan 22;321(3):277-287. doi: 10.1001/jama.2018.20578.
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Spontaneous sublingual space hematoma secondary to hypertension: A case report and review of literature.
高血压继发自发性舌下间隙血肿:一例报告并文献复习
Natl J Maxillofac Surg. 2015 Jan-Jun;6(1):96-8. doi: 10.4103/0975-5950.168223.
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Association of aspirin use with major bleeding in patients with and without diabetes.阿司匹林的使用与糖尿病患者和非糖尿病患者的大出血风险的相关性。
JAMA. 2012 Jun 6;307(21):2286-94. doi: 10.1001/jama.2012.5034.
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Massive sublingual hematoma secondary to anticoagulant therapy complicated by a traumatic denture: a case report.抗凝治疗继发巨大舌下血肿并伴有外伤性义齿:一例报告
J Med Case Rep. 2012 Apr 10;6:105. doi: 10.1186/1752-1947-6-105.
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Upper airway obstruction by sublingual hematoma: a complication of anticoagulation therapy with acenocoumarol.舌下血肿导致上气道梗阻:醋硝香豆素抗凝治疗的一种并发症。
Am J Otolaryngol. 2006 Mar-Apr;27(2):129-32. doi: 10.1016/j.amjoto.2005.07.013.
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Spontaneous sublingual hematoma as a complication of severe hypertension: first report of a case.自发性舌下血肿作为重度高血压的一种并发症:首例病例报告
Ear Nose Throat J. 2002 Aug;81(8):576-8.
8
Treatment of a sublingual hematoma with medicinal leeches: report of case.药用水蛭治疗舌下血肿:病例报告
J Oral Maxillofac Surg. 1996 Jan;54(1):101-3. doi: 10.1016/s0278-2391(96)90314-6.