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儿童血液恶性肿瘤治疗后晚期效应和毒性的筛查及干预策略。

Screening and interventional strategies for the late effects and toxicities of hematological malignancy treatments in pediatric survivors.

机构信息

Department of Hematology and Oncology, Nagano Children's Hospital, Azumino, Japan.

出版信息

Expert Rev Hematol. 2024 Jul;17(7):313-327. doi: 10.1080/17474086.2024.2370559. Epub 2024 Jun 25.

DOI:10.1080/17474086.2024.2370559
PMID:38899398
Abstract

INTRODUCTION

Advancements in pediatric cancer treatment have increased patient survival rates; however, childhood cancer survivors may face long-term health challenges due to treatment-related effects on organs. Regular post-treatment surveillance and early intervention are crucial for improving the survivors' quality of life and long-term health outcomes. The present paper highlights the significance of late effects in childhood cancer survivors, particularly those with hematologic malignancies, stressing the importance of a vigilant follow-up approach to ensure better overall well-being.

AREAS COVERED

This article provides an overview of the treatment history of childhood leukemia and lymphoma as well as outlines the emerging late effects of treatments. We discuss the various types of these complications and their corresponding risk factors.

EXPERT OPINION

Standardizing survivorship care in pediatric cancer aims to improve patient well-being by optimizing their health outcomes and quality of life. This involves early identification and intervention of late effects, requiring collaboration among specialists, nurses, and advocates, and emphasizing data sharing and international cooperation.

摘要

简介

儿科癌症治疗的进步提高了患者的存活率;然而,由于治疗对器官的影响,儿童癌症幸存者可能面临长期的健康挑战。定期的治疗后监测和早期干预对于提高幸存者的生活质量和长期健康结果至关重要。本文强调了儿童癌症幸存者(特别是血液系统恶性肿瘤幸存者)晚期效应的重要性,强调了采用警惕性随访方法的重要性,以确保整体健康状况更好。

涵盖领域

本文概述了儿童白血病和淋巴瘤的治疗史,并概述了治疗后出现的新的晚期效应。我们讨论了这些并发症的各种类型及其相应的危险因素。

专家意见

标准化儿童癌症的生存护理旨在通过优化患者的健康结果和生活质量来提高患者的幸福感。这需要早期识别和干预晚期效应,需要专家、护士和倡导者之间的合作,并强调数据共享和国际合作。

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Expert Rev Hematol. 2024 Jul;17(7):313-327. doi: 10.1080/17474086.2024.2370559. Epub 2024 Jun 25.
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