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青光眼和高眼压症患者虚拟现实头动仪周边重复性研究。

Repeatability of a Virtual Reality Headset Perimeter in Glaucoma and Ocular Hypertensive Patients.

机构信息

Genentech, Inc., South San Francisco, CA, USA.

Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.

出版信息

Transl Vis Sci Technol. 2024 Jun 3;13(6):14. doi: 10.1167/tvst.13.6.14.

Abstract

PURPOSE

The VisuALL S is an automated, static threshold, virtual reality-based perimeter for mobile evaluation of the visual field. We examined same-day and 3-month repeatability.

METHODS

Adult participants with a diagnosis of glaucoma or ocular hypertension underwent two VisuALL 24-2 Normal T- Full threshold strategy tests at baseline and one additional exam at 3 months for each eligible eye. Spearman, intraclass correlation coefficients (ICCs), and Bland-Altman plots were used to assess the correlation of individual point sensitivities and mean deviation (MD) among three tests.

RESULTS

Eighty-eight eyes (44 participants) were included. Average age was 68.1 ± 14.3 years, and 60.7% were male. VisuALL MD was highly correlated between tests (intravisit: r = 0.89, intervisit: r = 0.82; P < 0.001 for both). Bland-Altman analysis showed an average difference in intravisit MD of -0.67 dB (95% confidence interval [CI], -6.04 to 4.71 dB) and -0.15 dB (95% CI, -8.04 to 7.73 dB) for intervisit exams. Eight-five percent of pointwise intravisit ICCs were above 0.75 (range, 0.63 to 0.93), and 65% of pointwise intervisit ICCs were above 0.75 (range, 0.55 to 0.91).

CONCLUSIONS

VisuALL demonstrated high correlation of MD between tests and good repeatability for individual point sensitivities among three tests in 3 months, except at the points around the blind spot and superiorly.

TRANSLATIONAL RELEVANCE

The preliminary reproducibility results for VisuALL are encouraging. Its portable design makes it a potentially useful tool for patients with glaucoma, enabling more frequent assessments both at home and in clinical settings.

摘要

目的

VisuALL S 是一种自动化的、静态阈值的虚拟现实周边设备,用于移动评估视野。我们检查了同日和 3 个月的可重复性。

方法

患有青光眼或高眼压症的成年参与者在基线时接受两次 VisuALL 24-2 正常 T-全阈值策略测试,每个符合条件的眼睛在 3 个月时额外进行一次检查。使用 Spearman 相关系数、组内相关系数(ICC)和 Bland-Altman 图来评估三次测试中个体点敏感性和平均偏差(MD)的相关性。

结果

纳入 88 只眼(44 名参与者)。平均年龄为 68.1±14.3 岁,60.7%为男性。VisuALL MD 在测试之间高度相关(日内:r=0.89,日间:r=0.82;均 P<0.001)。Bland-Altman 分析显示日内 MD 的平均差异为-0.67dB(95%置信区间[CI],-6.04 至 4.71dB)和-0.15dB(95%CI,-8.04 至 7.73dB)。85%的点内日内 ICC 大于 0.75(范围,0.63 至 0.93),65%的点间日内 ICC 大于 0.75(范围,0.55 至 0.91)。

结论

VisuALL 显示 MD 在测试之间具有高度相关性,在 3 个月内三次测试中单个点敏感性具有良好的可重复性,但在盲点和上方周围的点除外。

翻译

VisuALL 在 3 个月内的测试中显示出 MD 之间具有高度相关性,并且对个体点敏感性具有良好的可重复性,但在盲点及其周围的点除外。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c4/11193066/2391d6846862/tvst-13-6-14-f001.jpg

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