Genentech, Inc., South San Francisco, CA, USA.
Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA.
Transl Vis Sci Technol. 2024 Jun 3;13(6):14. doi: 10.1167/tvst.13.6.14.
The VisuALL S is an automated, static threshold, virtual reality-based perimeter for mobile evaluation of the visual field. We examined same-day and 3-month repeatability.
Adult participants with a diagnosis of glaucoma or ocular hypertension underwent two VisuALL 24-2 Normal T- Full threshold strategy tests at baseline and one additional exam at 3 months for each eligible eye. Spearman, intraclass correlation coefficients (ICCs), and Bland-Altman plots were used to assess the correlation of individual point sensitivities and mean deviation (MD) among three tests.
Eighty-eight eyes (44 participants) were included. Average age was 68.1 ± 14.3 years, and 60.7% were male. VisuALL MD was highly correlated between tests (intravisit: r = 0.89, intervisit: r = 0.82; P < 0.001 for both). Bland-Altman analysis showed an average difference in intravisit MD of -0.67 dB (95% confidence interval [CI], -6.04 to 4.71 dB) and -0.15 dB (95% CI, -8.04 to 7.73 dB) for intervisit exams. Eight-five percent of pointwise intravisit ICCs were above 0.75 (range, 0.63 to 0.93), and 65% of pointwise intervisit ICCs were above 0.75 (range, 0.55 to 0.91).
VisuALL demonstrated high correlation of MD between tests and good repeatability for individual point sensitivities among three tests in 3 months, except at the points around the blind spot and superiorly.
The preliminary reproducibility results for VisuALL are encouraging. Its portable design makes it a potentially useful tool for patients with glaucoma, enabling more frequent assessments both at home and in clinical settings.
VisuALL S 是一种自动化的、静态阈值的虚拟现实周边设备，用于移动评估视野。我们检查了同日和 3 个月的可重复性。
患有青光眼或高眼压症的成年参与者在基线时接受两次 VisuALL 24-2 正常 T-全阈值策略测试，每个符合条件的眼睛在 3 个月时额外进行一次检查。使用 Spearman 相关系数、组内相关系数（ICC）和 Bland-Altman 图来评估三次测试中个体点敏感性和平均偏差（MD）的相关性。
纳入 88 只眼（44 名参与者）。平均年龄为 68.1±14.3 岁，60.7%为男性。VisuALL MD 在测试之间高度相关（日内：r=0.89，日间：r=0.82；均 P<0.001）。Bland-Altman 分析显示日内 MD 的平均差异为-0.67dB（95%置信区间[CI]，-6.04 至 4.71dB）和-0.15dB（95%CI，-8.04 至 7.73dB）。85%的点内日内 ICC 大于 0.75（范围，0.63 至 0.93），65%的点间日内 ICC 大于 0.75（范围，0.55 至 0.91）。
VisuALL 显示 MD 在测试之间具有高度相关性，在 3 个月内三次测试中单个点敏感性具有良好的可重复性，但在盲点和上方周围的点除外。
VisuALL 在 3 个月内的测试中显示出 MD 之间具有高度相关性，并且对个体点敏感性具有良好的可重复性，但在盲点及其周围的点除外。
