[人体脂肪组织中的脂肪分解（作者译）]
[Lipolysis in human adipose tissue (author's transl)].
作者信息
Lisch H J, Schwammberger K, Sailer S
出版信息
Wien Klin Wochenschr. 1976 Jan 23;88(2):60-2.
Lipolytic activity was measured under different conditions in isolated fat cells and homogenates of human adipose tissue of the greater omentum. It was demonstrated that lipolysis took place in isolated fat cells at an optimum pH of 7.4 and was markedly stimulated by noradrenaline, but not by blood serum. By contrast lipolysis was significantly stimulated by blood serum, but not by noradrenaline, in homogenates of adipose tissue. Serum-stimulated lipolysis exhibited optimum activity at pH 8 and was inhibited by 1M sodium chloride. It is concluded that lipolytic activity in isolated fat cells can mainly be ascribed to the action of hormone-sensitive lipase, whereas lipolysis in homogenates of adipose tissue in the presence of serum is mostly regulated by lipoprotein lipase.
在不同条件下，对分离的脂肪细胞和大网膜人脂肪组织匀浆的脂解活性进行了测定。结果表明，分离的脂肪细胞在最适pH值7.4时发生脂解，去甲肾上腺素可显著刺激脂解，但血清不能。相比之下，脂肪组织匀浆中的脂解受到血清的显著刺激，但不受去甲肾上腺素的刺激。血清刺激的脂解在pH值8时表现出最佳活性，并受到1M氯化钠的抑制。结论是，分离的脂肪细胞中的脂解活性主要归因于激素敏感性脂肪酶的作用，而在血清存在下脂肪组织匀浆中的脂解主要由脂蛋白脂肪酶调节。
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