Vorob'ev L P, Samsonov A A
Ter Arkh. 1985;57(2):52-5.
A study was made of microcirculation in patients with peptic ulcer of the duodenum during exacerbation and after combined antiulcerous therapy including trental that improves microcirculation and rheology of the blood. The data obtained point to the presence in the majority of patients of pronounced microcirculatory disorders during exacerbation. The degree of the disorders depended on the disease standing, acuity of the painful syndrome and the size of the ulcer. The use of trental as a constituent part of therapy led to significant correction of the altered parameters of microcirculation and reduction of the time of ulcer cicatrization. Application of trental entailed a reduction in secretory function of the gastric glands according to the data of fractional exploration. It is recommended that trental may be included into combined therapy of peptic ulcer of the duodenum.
对十二指肠消化性溃疡患者在病情加重期以及采用包括能改善微循环和血液流变学的曲克芦丁在内的联合抗溃疡治疗后进行了微循环研究。所获数据表明，大多数患者在病情加重期存在明显的微循环障碍。这些障碍的程度取决于疾病状况、疼痛综合征的严重程度以及溃疡的大小。将曲克芦丁用作治疗的组成部分可显著纠正微循环改变的参数，并缩短溃疡愈合时间。根据分段探查的数据，应用曲克芦丁会使胃腺的分泌功能降低。建议将曲克芦丁纳入十二指肠消化性溃疡的联合治疗中。
