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[各种肺部疾病中蛋白酶活性及结缔组织成分抗体水平]

[Protease activity and the level of antibodies to connective tissue elements in various lung diseases].

作者信息

Vinnik L A, Gerovich L M

出版信息

Ter Arkh. 1985;57(3):83-5.

PMID:3890258
Abstract

Altogether 274 patients with different pulmonary diseases were examined for the activity of trypsin and elastase of the blood and the level of their inhibitors. The concentration of antibodies to collagen and elastin was also measured. In acute chronic pneumonia or exacerbation, the activity of the enzymes increased, the concentration of antibodies to collagen and elastin rose. In acute pneumonia, the titer of antibodies to collagen and elastin persisted for 1-1.5 months, in CNPD and tuberculosis for 4-8 months.

摘要

共对274例患有不同肺部疾病的患者进行了血液中胰蛋白酶和弹性蛋白酶活性及其抑制剂水平的检测。还测定了抗胶原蛋白和弹性蛋白抗体的浓度。在急性慢性肺炎或病情加重时,酶的活性增加,抗胶原蛋白和弹性蛋白抗体的浓度升高。在急性肺炎中,抗胶原蛋白和弹性蛋白抗体的滴度持续1 - 1.5个月,在慢性阻塞性肺疾病(COPD)和肺结核中持续4 - 8个月。

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