休闲相关体力活动的益处，以及久坐时间与高血压和 2 型糖尿病风险之间的关联。

Benefits of leisure-related physical activity and association between sedentary time and risk for hypertension and type 2 diabetes.

机构信息

Research Division, Institute of Mental Health, Singapore.

Admiralty Medical Centre, Khoo Teck Puat Hospital, Singapore.

出版信息

Ann Acad Med Singap. 2023 Apr 27;52(4):172-181. doi: 10.47102/annals-acadmedsg.2022399.

DOI:10.47102/annals-acadmedsg.2022399

PMID:38904530

Abstract

INTRODUCTION

Lifestyle modifications can reduce the risk of type 2 diabetes mellitus (T2DM) and hypertension. Our study investigated whether domain-specific physical activity (such as work, transport and leisure) and sedentary behaviour were associated with T2DM and hypertension, and whether these associations were moderated by sex and age.

METHOD

For this cross-sectional study, data were obtained from a population survey in Singapore (n=2,867) conducted from February 2019 to March 2020. T2DM and hypertension were self-reported. Global physical activity questionnaire was used to assess domain-specific physical activity (in metabolic equivalent of task [MET]-minutes) and sedentary time (in hours). Logistic regression models were generated to examine the abovementioned associations, and adjusted for age, sex, education, ethnicity, personal income, body mass index, diet and hypertension/diabetes. Interaction terms were included individually to investigate whether age and sex moderated the associations.

RESULTS

Individuals with >826 MET-minutes of leisure-related physical activity per week had lower odds of having T2DM (odds ratio [OR] 0.46, 95% confidence interval [CI] 0.24-0.86) and hypertension (OR 0.59, 95% CI 0.37-0.94) than those with no leisure-related physical activity. Individuals with >8 hours of sedentary time daily had higher odds of having hypertension (OR 1.69, 95% CI 1.06-2.69) than those with 0-5 hours of sedentary time. Logistic regression models including interaction terms showed that the association between leisure-related physical activity and hypertension was significant for those aged 18-34 (OR 0.15, 95% CI 0.03-0.66) and 50-64 years (OR 0.44, 95% CI 0.21-0.91). The association between sedentary time and hypertension was significant for those aged 18-34 years (OR 15.07, 95% CI 1.69-133.92).

CONCLUSION

Our results support the widespread promotion of an active lifestyle to lower the prevalence of diabetes and hypertension in Singapore.

摘要

简介

生活方式的改变可以降低 2 型糖尿病（T2DM）和高血压的风险。我们的研究调查了特定领域的体力活动（如工作、交通和休闲）和久坐行为是否与 T2DM 和高血压有关，以及这些关联是否受到性别和年龄的调节。

方法

本横断面研究的数据来自 2019 年 2 月至 2020 年 3 月在新加坡进行的一项人群调查（n=2867）。T2DM 和高血压均为自我报告。使用全球体力活动问卷评估特定领域的体力活动（代谢当量[MET]-分钟）和久坐时间（小时）。生成逻辑回归模型以检查上述关联，并根据年龄、性别、教育、种族、个人收入、体重指数、饮食和高血压/糖尿病进行调整。单独纳入交互项，以调查年龄和性别是否调节关联。

结果

每周进行>826 MET 分钟休闲相关体力活动的个体患 T2DM（比值比[OR]0.46，95%置信区间[CI]0.24-0.86）和高血压（OR 0.59，95%CI 0.37-0.94）的可能性低于不进行休闲相关体力活动的个体。每天有>8 小时久坐时间的个体患高血压的几率（OR 1.69，95%CI 1.06-2.69）高于每天有 0-5 小时久坐时间的个体。纳入交互项的逻辑回归模型显示，对于 18-34 岁（OR 0.15，95%CI 0.03-0.66）和 50-64 岁（OR 0.44，95%CI 0.21-0.91）的个体，休闲相关体力活动与高血压之间的关联具有统计学意义。对于 18-34 岁的个体，久坐时间与高血压之间的关联具有统计学意义（OR 15.07，95%CI 1.69-133.92）。