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Vertical and horizontal geographic atrophy - A concept to overcome the current structure-function paradox.

作者信息

Siedlecki Jakob, Priglinger Siegfried

机构信息

Department of Ophthalmology, LMU University Hospital, LMU Munich, Munich, Germany.

出版信息

Eye (Lond). 2024 Oct;38(14):2665-2667. doi: 10.1038/s41433-024-03174-2. Epub 2024 Jun 21.

DOI:10.1038/s41433-024-03174-2
PMID:38907017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11427470/
Abstract
摘要

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本文引用的文献

1
Macular Sensitivity Endpoints in Geographic Atrophy: Exploratory Analysis of Chroma and Spectri Clinical Trials.地图样萎缩中的黄斑敏感性终点：色度和光谱临床试验的探索性分析。
Ophthalmol Sci. 2023 Jun 12;4(1):100351. doi: 10.1016/j.xops.2023.100351. eCollection 2024 Jan-Feb.
2
Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials.培格司他单抗治疗与年龄相关的黄斑变性（OAKS 和 DERBY）相关的地图状萎缩：两项多中心、随机、双盲、假对照、3 期临床试验。
Lancet. 2023 Oct 21;402(10411):1434-1448. doi: 10.1016/S0140-6736(23)01520-9.
3
The Issue of End Point Discordance in Dry Age-Related Macular Degeneration: How Might Clinical Trials Demonstrate a Functional Benefit?干性年龄相关性黄斑变性中的终点不一致问题：临床试验如何证明功能获益？
Ophthalmology. 2023 Sep;130(9):890-892. doi: 10.1016/j.ophtha.2023.05.020. Epub 2023 Jun 6.
4
Two potentially distinct pathways to geographic atrophy in age-related macular degeneration characterized by quantitative fundus autofluorescence.两种定量眼底自发荧光特征的年龄相关性黄斑变性中地理萎缩的潜在不同途径。
Eye (Lond). 2023 Aug;37(11):2281-2288. doi: 10.1038/s41433-022-02332-8. Epub 2023 Jan 9.
5
The Effect of Pegcetacoplan Treatment on Photoreceptor Maintenance in Geographic Atrophy Monitored by Artificial Intelligence-Based OCT Analysis.基于人工智能的 OCT 分析观察到培格司他单抗治疗对地理萎缩中感光细胞维持的影响。
Ophthalmol Retina. 2022 Nov;6(11):1009-1018. doi: 10.1016/j.oret.2022.05.030. Epub 2022 Jun 3.
6
SUBRETINAL DRUSENOID DEPOSITS AND SOFT DRUSEN: Are They Markers for Distinct Retinal Diseases?视网膜下硬性脂滴沉积和软性脂滴：它们是不同视网膜疾病的标志物吗？
Retina. 2022 Jul 1;42(7):1311-1318. doi: 10.1097/IAE.0000000000003460.
7
Inferred retinal sensitivity in recessive Stargardt disease using machine learning.使用机器学习推断隐性斯塔加特病的视网膜敏感性。
Sci Rep. 2021 Jan 14;11(1):1466. doi: 10.1038/s41598-020-80766-4.
8
Validation of an Automated Quantification of Relative Ellipsoid Zone Reflectivity on Spectral Domain-Optical Coherence Tomography Images.光谱域光学相干断层扫描图像上相对椭球区反射率自动定量的验证
Transl Vis Sci Technol. 2020 Oct 14;9(11):17. doi: 10.1167/tvst.9.11.17. eCollection 2020 Oct.
9
Visual Function Decline Resulting from Geographic Atrophy: Results from the Chroma and Spectri Phase 3 Trials.由地理萎缩导致的视觉功能下降：Chroma 和 Spectri 第三阶段试验的结果。
Ophthalmol Retina. 2020 Jul;4(7):673-688. doi: 10.1016/j.oret.2020.01.019. Epub 2020 Jan 31.
10
Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration.与年龄相关性黄斑变性相关的地图状萎缩区域的光敏感性。
Invest Ophthalmol Vis Sci. 2019 Sep 3;60(12):3992-4001. doi: 10.1167/iovs.19-27178.