Santos Adenilson Dos, Oliveira Alan Santos, Carvalho Mikaella Tuanny Bezerra, Barreto André Sales, Quintans Jullyana de Souza Siqueira, Quintans Júnior Lucindo José, Barreto Rosana de Souza Siqueira
Graduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Graduate Program in Health Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil; Department of Health Education, Federal University of Sergipe, Lagarto, Sergipe, Brazil.
J Ethnopharmacol. 2024 Oct 28;333:118478. doi: 10.1016/j.jep.2024.118478. Epub 2024 Jun 21.
H. pectinata (L.) Poit, popularly known as "sambacaitá" or "canudinho", is a plant endemic to north-eastern Brazil. Its aerial parts, leaves and flowers have traditionally been used to treat gastrointestinal disorders, rhinopharyngitis, nasal congestion, bacterial and fungal infections, fever, colic, inflammation, and pain.
The aim of this review was to provide information on the botanical characteristics, ethnomedicinal uses, phytochemistry and biological-pharmacological activities of H. pectinata.
This systematic review followed the Cochrane Handbook Collaboration and the PRISMA guidelines. The review question was what are the biological-pharmacological activities of H. pectinata presented in non-clinical studies. The search for articles was conducted in the Medline (via PubMed), Embase, Web of Science, Scopus, Virtual Health Library, SciELO, Google Scholar and the Brazilian Digital Library of Theses and Dissertations databases. Two reviewers independently selected the studies that met the inclusion criteria, extracted the data, and assessed the risk of bias of the included studies.
39 articles were included in this review, of which 19 reported in vitro experiments, 16 in vivo studies and 4 in vivo and in vitro experiments. H. pectinata is a plant widely used in folk medicine in north-eastern Brazil for the treatment of various ailments, such as respiratory diseases, gastrointestinal disorders, bacterial and fungal infections, and general inflammation. Supporting its popular use, several in vitro and in vivo pharmacological investigations of the essential oil and extract of H. pectinata have demonstrated their anti-inflammatory, antinociceptive, antioxidant, antidepressant, anticancer, hepatoregenerative, healing, and antimicrobial activities. H. pectinata has been reported to contain 75 bioactive constituents, comprising 9 flavonoids, 54 terpenes, and 12 other compounds.
H. pectinata is a plant commonly used in traditional medicine. Phytochemically, it contains several bioactive constituents, including terpenes and flavonoids, and has been shown to have antinociceptive, anti-inflammatory, antimicrobial and antitumour activity, as well as hepatorregenerative and healing effects, and low toxicity.
海芒果（H. pectinata (L.) Poit），俗称“sambacaitá”或“canudinho”，是巴西东北部特有的一种植物。其地上部分、叶子和花朵传统上被用于治疗胃肠道疾病、鼻咽炎、鼻塞、细菌和真菌感染、发烧、绞痛、炎症和疼痛。
本综述的目的是提供有关海芒果的植物学特征、民族药用用途、植物化学和生物药理学活性的信息。
本系统综述遵循Cochrane手册协作组和PRISMA指南。综述问题是非临床研究中报道的海芒果的生物药理学活性有哪些。在Medline（通过PubMed）、Embase、科学引文索引、Scopus、虚拟健康图书馆、SciELO、谷歌学术以及巴西论文和学位论文数字图书馆数据库中进行文献检索。两名评审员独立选择符合纳入标准的研究，提取数据，并评估纳入研究的偏倚风险。
本综述纳入了39篇文章，其中19篇报道了体外实验，16篇报道了体内研究，4篇报道了体内和体外实验。海芒果是巴西东北部民间医学中广泛用于治疗各种疾病的一种植物，如呼吸系统疾病、胃肠道疾病、细菌和真菌感染以及全身性炎症。支持其广泛应用的是，对海芒果精油和提取物的多项体外和体内药理学研究已证明它们具有抗炎、镇痛、抗氧化、抗抑郁、抗癌、肝再生、愈合和抗菌活性。据报道，海芒果含有75种生物活性成分，包括9种黄酮类化合物、54种萜类化合物和12种其他化合物。
海芒果是传统医学中常用的一种植物。从植物化学角度来看，它含有多种生物活性成分，包括萜类化合物和黄酮类化合物，并已显示出具有镇痛、抗炎、抗菌和抗肿瘤活性，以及肝再生和愈合作用，且毒性较低。
