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卵圆孔未闭和房间隔缺损。

Patent Foramen Ovale and Atrial Septal Defect.

机构信息

Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.

Houston Methodist DeBakey Heart & Vascular Center, Houston, TX, USA.

出版信息

Cardiol Clin. 2024 Aug;42(3):417-431. doi: 10.1016/j.ccl.2024.02.019. Epub 2024 Mar 28.

Abstract

Patent foramen ovale (PFO) and atrial septal defects (ASDs) are two types of interatrial communications with unique clinical presentations and management strategies. The PFO is a normal part of fetal development that typically closes shortly after birth but may persist in as many as 25% to 30% of adults. The communication between atria may result in paradoxic embolism and embolic stroke. On the other hand, ASDs (anatomically defined as secundum, primum, sinus venosus, and coronary sinus in order of prevalence) typically result in right heart volume overload and are often associated with other congenital defects. The diagnostic methods, treatment options including surgical and percutaneous approaches, and potential complications are described. Both conditions underline the significance of precise diagnosis and appropriate management to mitigate risks and ensure optimal patient outcomes.

摘要

卵圆孔未闭(PFO)和房间隔缺损(ASD)是两种类型的房间隔交通,具有独特的临床表现和管理策略。PFO 是胎儿发育过程中的正常部分,通常在出生后不久就会闭合,但在多达 25%至 30%的成年人中可能会持续存在。心房之间的沟通可能导致反常栓塞和栓塞性中风。另一方面,ASD(解剖学上定义为按照流行程度依次为继发孔、原发孔、静脉窦和冠状窦)通常导致右心容量超负荷,并且常与其他先天性缺陷相关。描述了诊断方法、包括手术和经皮途径的治疗选择以及潜在并发症。这两种情况都强调了精确诊断和适当管理的重要性,以降低风险并确保患者获得最佳结果。

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