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对一种独特的硬脊膜内、髓外表现的脊髓血管球瘤的诊断与治疗见解——系统评价

Diagnostic and Therapeutic Insights into Spinal Glomangioma of a Unique Intradural, Extramedullary Presentation-Systematic Review.

作者信息

Czyżewski Wojciech, Litak Jakub, Pasierb Barbara, Piątek Paula, Turek Michał, Banach Lech, Turek Grzegorz, Torres Kamil, Staśkiewicz Grzegorz

机构信息

Department of Neurosurgery, Maria Sklodowska-Curie National Research Institute of Oncology, ul. W.K. 7 Roentgena 5, 02-781 Warsaw, Poland.

Department of Didactics and Medical Simulation, Medical University of Lublin, 20-954 Lublin, Poland.

出版信息

Diseases. 2024 Jun 20;12(6):132. doi: 10.3390/diseases12060132.

DOI:10.3390/diseases12060132
PMID:38920564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11203330/
Abstract

Contemporary literature lacks examples of intradural, extramedullary spinal glomangiomas. Moreover, glomus tumors in general are exceedingly rare among benign spinal tumors and are mostly located within epidural space or within intervertebral foramen, and only a few cases have been documented to date. This report provides a detailed analysis of the clinical presentation, imaging characteristics, surgical intervention, and pathological findings of a 45-year-old patient experiencing progressive locomotor deterioration. The tumor was surgically excised, and subsequent histological examination identified it as a representative of glomus tumors-a glomangioma. Notably, this represents a unique case as it was the first example of such a tumor being discovered intradurally. Radical surgical excision remains the modality of choice in most benign spinal tumors of this localization. Although the malignant transformation of glomus tumors within the spine has not been documented thus far, cases have arisen in other areas. Consequently, we will investigate potential oncological treatments for cases with malignant potential and highlight advancements in surgical techniques for benign intradural spinal tumors.

摘要

当代文献中缺乏硬脊膜内、髓外脊髓血管球瘤的病例。此外,血管球瘤在良性脊柱肿瘤中极为罕见,大多位于硬膜外间隙或椎间孔内,迄今为止仅有少数病例报道。本报告详细分析了一名45岁进行性运动功能恶化患者的临床表现、影像学特征、手术干预及病理结果。该肿瘤经手术切除,随后的组织学检查确定其为血管球瘤的典型代表——血管球血管瘤。值得注意的是,这是一个独特的病例,因为它是首例在硬脊膜内发现的此类肿瘤。根治性手术切除仍是大多数此类定位的良性脊柱肿瘤的首选治疗方式。尽管迄今为止尚未有脊柱内血管球瘤发生恶性转化的报道,但在其他部位已有此类病例出现。因此,我们将研究针对具有恶性潜能病例的潜在肿瘤治疗方法,并强调良性硬脊膜内脊柱肿瘤手术技术的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/e8ea9fb83d0b/diseases-12-00132-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/711c24ab62fe/diseases-12-00132-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/adac8dbfdf45/diseases-12-00132-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/8a13b43500dc/diseases-12-00132-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/e8ea9fb83d0b/diseases-12-00132-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/711c24ab62fe/diseases-12-00132-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/adac8dbfdf45/diseases-12-00132-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/8a13b43500dc/diseases-12-00132-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d009/11203330/e8ea9fb83d0b/diseases-12-00132-g004.jpg

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本文引用的文献

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Unilateral Biportal Endoscopy for the Resection of Thoracic Intradural Extramedullary Tumors: Technique Case Report and Literature Review.单孔双镜技术用于胸段硬脊膜外髓外肿瘤切除:技术、病例报告及文献综述
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Pericytes as the Orchestrators of Vasculature and Adipogenesis.
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Genes (Basel). 2024 Jan 19;15(1):126. doi: 10.3390/genes15010126.
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Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury.星形胶质细胞:创伤性脑损伤治疗的新靶点
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The clinicopathologic and immunohistochemical features of 60 cutaneous glomus tumor: a retrospective case series study.60 例皮肤血管球瘤的临床病理及免疫组化特征:回顾性病例系列研究。
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Glomus tumour: an institutional experience of 31 cases.血管球瘤:31 例机构经验。
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A case of solitary digital glomus tumor associated with neurofibromatosis type 1.一例与1型神经纤维瘤病相关的孤立性指(趾)部血管球瘤。
SAGE Open Med Case Rep. 2023 Aug 21;11:2050313X231193984. doi: 10.1177/2050313X231193984. eCollection 2023.
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Primary Benign Neoplasms of the Spine.脊柱原发性良性肿瘤
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