Gaspari Arianna, Vaccari Giulia, Arturi Federica, Melegari Gabriele, Baroni Stefano
Department of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria di Modena, Via del Pozzo 71, 41125 Modena, Italy.
School of Anesthesia and Intensive Care, University of Modena and Reggio Emilia, Via del Pozzo 71, 41125 Modena, Italy.
Neurol Int. 2024 Jun 20;16(3):663-672. doi: 10.3390/neurolint16030050.
In patients with acute ischemic stroke, the standard of care is to perform intra-arterial endovascular thrombectomy in addition to intravenous thrombolysis. In this study, we investigated the different anesthetic techniques chosen for this procedure and clinical outcomes.
Patients undergoing endovascular procedures were divided into three groups. The first group consisted of patients who received general anesthesia, the second group underwent the procedure under conscious sedation and local anesthesia at the catheter insertion site, and lastly the third group included patients who received only local anesthesia at the catheter insertion site, without sedation.
During the endovascular procedure, we did not notice significant differences in vital parameters, in particular the mean blood pressure (MAP) between patients treated with different types of anesthesia. Also, the duration of the revascularization did not show significant differences between the three groups. The main point is the absence of differences in terms of functional and clinical outcomes, using various scores as reference, such as the National Institutes of Health Stroke Scale (NIHSS) score at 7 days, NIHSS and Modified Rankin Scale (MRS) at time of discharge, and MRS after 3 months. These scores did not show significant differences in groups treated with different types of anesthesia.
The rate of success of the revascularization procedure is almost overlapping between patients treated with conscious sedation and general anesthesia. In addition, we did not notice significant differences between groups in terms of functional and clinical outcomes. Considering the possible usefulness of applying conscious sedation, at OCSAE of Baggiovara, an internal protocol for conscious sedation was introduced to standardize the treatment in patients undergoing endovascular procedures.
在急性缺血性中风患者中,护理标准是除静脉溶栓外还进行动脉内血管内血栓切除术。在本研究中,我们调查了为此手术选择的不同麻醉技术及临床结果。
接受血管内手术的患者分为三组。第一组由接受全身麻醉的患者组成,第二组在导管插入部位在清醒镇静和局部麻醉下进行手术,最后第三组包括仅在导管插入部位接受局部麻醉且无镇静的患者。
在血管内手术过程中,我们未注意到不同类型麻醉治疗的患者在生命体征参数,特别是平均血压(MAP)方面存在显著差异。此外,三组之间血管再通持续时间也未显示出显著差异。重点是在使用各种评分作为参考时,如7天时的美国国立卫生研究院卒中量表(NIHSS)评分、出院时的NIHSS和改良Rankin量表(MRS)以及3个月后的MRS,不同类型麻醉治疗的组在功能和临床结果方面没有差异。这些评分在不同类型麻醉治疗的组中未显示出显著差异。
清醒镇静和全身麻醉治疗的患者血管再通手术成功率几乎重叠。此外,我们未注意到各组在功能和临床结果方面存在显著差异。考虑到应用清醒镇静的可能益处,在巴焦瓦拉的OCSAE,引入了一项清醒镇静内部协议,以规范接受血管内手术患者的治疗。