Fingerle Michele, Salaorni Sebastiano, Pietrobelli Angelo, Piacentini Giorgio, Banzato Claudia, Pecoraro Luca
Pediatric Unit, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, 37126 Verona, Italy.
Children (Basel). 2024 Jun 7;11(6):707. doi: 10.3390/children11060707.
Immunological illnesses related to wheat represent an epidemiologically relevant phenomenon at a pediatric age. The term "Wheat-related disorders" involves a spectrum of diseases: celiac disease, IgE-mediated wheat allergy, non-IgE mediated wheat allergy, wheat-related eosinophilic esophagitis, and non-celiac gluten sensitivity. Their pathogenesis is different. At the same time, wheat represents their common point. This article aims to the state-of-the-art and new clinical evidence in pediatric age.
与小麦相关的免疫性疾病在儿童时期是一种具有流行病学相关性的现象。“与小麦相关的疾病”这一术语涵盖了一系列疾病:乳糜泻、IgE介导的小麦过敏、非IgE介导的小麦过敏、与小麦相关的嗜酸性食管炎以及非乳糜泻性麸质敏感。它们的发病机制各不相同。同时,小麦是它们的共同点。本文旨在阐述儿童时期的最新研究状况和新的临床证据。