Lunguț Emilia Furdu, Antal Claudia, Turcu Suzana, Varlas Valentin-Nicolae, Filipescu Alexandru George, Balescu Irina, Bacalbașa Nicolae, Gorecki Gabriel-Petre
Department of Neurology, Faculty of Medicine, "Titu Maiorescu" University, 031593 Bucharest, Romania.
Department of Neurology, CF2 Clinical Hospital, 011464 Bucharest, Romania.
J Clin Med. 2024 Jun 7;13(12):3364. doi: 10.3390/jcm13123364.
Migraine is one of the most common diseases in highly developed countries, being even more common than diabetes and asthma. Migraines can affect emotional, social, and physical wellbeing as well as professional life. The most common symptoms are severe headaches associated with nausea, vomiting, photophobia and sonophobia, difficulty concentrating, sensitivity and emotional disorders. Many studies have been published to establish the best migraine-management drugs, but not many of them refer to plant extracts, which have been given more attention by patients lately. Among these generically called herbal medicines, the effect of tussilago hybrida standardized extract has been studied since the early twenties. This stands as the fundamental component of Neurasites and the reason for research on materials and methods, results on treatment schemes for diminishing migraine attack features, as well as migraine prevention. There are two directions of research (herbal and placebo medicine) considered to be of interest due to the actual trend toward natural medicine and against chemicals and associated drugs. For quantitative research, the research tool used was that of the Neurasites Questionnaire Survey (NQS). The obtained results prove the efficacy of treatment by reducing the duration of headache attacks, diminishing pain intensity and decreasing the frequency of migraine episodes. Further research development should focus on other dosages and treatment schemes and on other similar natural products to be used in migraine attack treatment.
偏头痛是高度发达国家最常见的疾病之一，甚至比糖尿病和哮喘更为普遍。偏头痛会影响情绪、社交和身体健康以及职业生活。最常见的症状是伴有恶心、呕吐、畏光和畏声、注意力难以集中、敏感和情绪障碍的严重头痛。已经发表了许多研究来确定最佳的偏头痛治疗药物，但其中涉及植物提取物的研究并不多，而植物提取物最近越来越受到患者的关注。在这些通常被称为草药的药物中，杂交款冬标准化提取物的效果自二十世纪二十年代初就开始被研究。它是Neurasites的基本成分，也是研究材料和方法的原因，以及关于减轻偏头痛发作特征的治疗方案和偏头痛预防的研究结果。由于目前倾向于使用天然药物而非化学药品及相关药物，有两个研究方向（草药和安慰剂药物）被认为是有意义的。对于定量研究，所使用的研究工具是Neurasites问卷调查（NQS）。获得的结果证明了通过缩短头痛发作持续时间、减轻疼痛强度和减少偏头痛发作频率进行治疗的有效性。进一步的研究发展应集中在其他剂量和治疗方案以及用于偏头痛发作治疗的其他类似天然产品上。
