Pyrpyris Nikolaos, Dimitriadis Kyriakos, Theofilis Panagiotis, Iliakis Panagiotis, Beneki Eirini, Pitsiori Daphne, Tsioufis Panagiotis, Shuvy Mony, Aznaouridis Konstantinos, Tsioufis Konstantinos
First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, 115 27 Athens, Greece.
Jesselson Integrated Heart Centre, Shaare Zedek Medical Center, Faculty of Medicine, Hebrew University, Jerusalem 9103102, Israel.
J Clin Med. 2024 Jun 16;13(12):3528. doi: 10.3390/jcm13123528.
Structural heart disease is increasingly prevalent in the general population, especially in patients of increased age. Recent advances in transcatheter structural heart interventions have gained a significant following and are now considered a mainstay option for managing stable valvular disease. However, the concept of transcatheter interventions has also been tested in acute settings by several investigators, especially in cases where valvular disease comes as a result of acute ischemia or in the context of acute decompensated heart failure. Tested interventions include both the mitral and aortic valve, mostly evaluating mitral transcatheter edge-to-edge repair and transcatheter aortic valve implantation, respectively. This review is going to focus on the use of acute structural heart interventions in the emergent setting, and it will delineate the available data and provide a meaningful discussion on the optimal patient phenotype and future directions of the field.
结构性心脏病在普通人群中越来越普遍,尤其是在老年患者中。经导管结构性心脏介入治疗的最新进展已获得广泛关注,现在被认为是治疗稳定瓣膜疾病的主要选择。然而,一些研究人员也在急性情况下对经导管介入治疗的概念进行了测试,特别是在瓣膜疾病由急性缺血引起或在急性失代偿性心力衰竭的情况下。测试的介入治疗包括二尖瓣和主动脉瓣,主要分别评估二尖瓣经导管缘对缘修复和经导管主动脉瓣植入术。本综述将重点关注急性结构性心脏介入治疗在紧急情况下的应用,阐述现有数据,并就最佳患者表型和该领域的未来方向进行有意义的讨论。