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挪威驯鹿血脂、肾上腺素、去甲肾上腺素、葡萄糖和胰岛素的季节性变化。

Seasonal changes in blood lipids, adrenaline, noradrenaline, glucose and insulin in Norwegian reindeer.

作者信息

Larsen T S, Lagercrantz H, Riemersma R A, Blix A S

出版信息

Acta Physiol Scand. 1985 May;124(1):53-9. doi: 10.1111/j.1748-1716.1985.tb07631.x.

DOI:10.1111/j.1748-1716.1985.tb07631.x
PMID:3893041
Abstract

Plasma concentrations of free fatty acids (FFA), glycerol, adrenaline, noradrenaline, glucose and insulin, as well as serum concentrations of triacylglycerols, total cholesterol and high density lipoprotein (HDL)-bound cholesterol, were measured at intervals during a I-year period in Norwegian reindeer. Free fatty acids and glycerol were high in January-March, low in April-July, and high again in August-September. Glucose was low in November-February and high but variable in March-October. Triacylglycerols, total and HDL-bound cholesterol were all low in November-March, but increasing in April and reaching a peak in August-September. Plasma noradrenaline and adrenaline did not change significantly throughout the year. Plasma insulin was low in October-April, increasing significantly from June-August/September. The seasonal changes in the serum concentrations of triacylglycerols, total and HDL-bound cholesterol, as well as the plasma concentration of glucose, coincided with the seasonal changes in food intake. Free fatty acids and, to some extent, glycerol were, in contrast, inversely related to feed intake. It is suggested that insulin may play an important role in the long-term regulation of fat mobilization, while the importance of catecholamines in this respect is questionable.

摘要

在为期1年的时间里,对挪威驯鹿的血浆游离脂肪酸(FFA)、甘油、肾上腺素、去甲肾上腺素、葡萄糖和胰岛素浓度,以及血清甘油三酯、总胆固醇和高密度脂蛋白(HDL)结合胆固醇浓度进行了定期测量。游离脂肪酸和甘油在1月至3月含量较高,4月至7月较低,8月至9月再次升高。葡萄糖在11月至2月含量较低,3月至10月较高但波动较大。甘油三酯、总胆固醇和HDL结合胆固醇在11月至3月均较低,但4月开始上升,并在8月至9月达到峰值。血浆去甲肾上腺素和肾上腺素全年无显著变化。血浆胰岛素在10月至4月含量较低,6月至8月/9月显著升高。血清甘油三酯、总胆固醇和HDL结合胆固醇浓度以及血浆葡萄糖浓度的季节性变化与食物摄入量的季节性变化一致。相比之下,游离脂肪酸以及在一定程度上甘油与采食量呈负相关。研究表明,胰岛素可能在脂肪动员的长期调节中发挥重要作用,而儿茶酚胺在这方面的重要性值得怀疑。

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