Pivetti-Pezzi P, De Liso P, Tamburi S, Luzi G, Sirianni M C, Palmisano L, Aiuti F
Ann Ophthalmol. 1985 Jun;17(6):327-31.
Thirty patients with herpetic keratitis were allocated to a double-blind trial with either local treatment plus placebo (control group) or local treatment plus thymostimulin (TS group). The follow-up at 24 months demonstrated a significant reduction of recurrence rate among patients receiving thymostimulin, along with a significant increase of sheep rosette-forming cells (E rosette). Furthermore, among patients with superficial keratitis, thymostimulin treatment resulted in a significantly quicker corneal re-epithelization than placebo. Thymostimulin seems to be a safe and helpful drug in the management of herpetic keratitis.
30例疱疹性角膜炎患者被分配至一项双盲试验，分别接受局部治疗加安慰剂（对照组）或局部治疗加胸腺刺激素（TS组）。24个月的随访显示，接受胸腺刺激素治疗的患者复发率显著降低，同时羊红细胞玫瑰花结形成细胞（E玫瑰花结）显著增加。此外，在浅层角膜炎患者中，胸腺刺激素治疗导致角膜上皮再形成明显快于安慰剂。胸腺刺激素似乎是治疗疱疹性角膜炎的一种安全且有效的药物。
