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桥脑髓鞘溶解症伴幻觉这一罕见表现：一例报告

Pontine myelinolysis with an uncommon manifestation of hallucination: a case report.

作者信息

Azzoni Andreia Braga Mota, Arca Vitor Maia, de Melo Eduardo Sousa

机构信息

Universidade Federal de Pernambuco, Hospital das Clínicas, Departamento de Neurologia, Recife PE, Brazil.

出版信息

Dement Neuropsychol. 2024 Jun 24;18:e20230068. doi: 10.1590/1980-5764-DN-2023-0068. eCollection 2024.

DOI:10.1590/1980-5764-DN-2023-0068
PMID:38933076
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11206230/
Abstract

This report aims to present an elderly woman with persistent delirium after hospitalization for lethargy secondary to hyponatremia. The diagnosis of pontine myelinolysis was made and there were no characteristic neurological manifestations such as pupillary changes or spastic tetraparesis. Hallucinations and personality changes were the clues to the diagnosis and should be considered an atypical manifestation of pontine myelinolysis.

摘要

本报告旨在介绍一名老年女性，因低钠血症继发嗜睡住院后出现持续性谵妄。诊断为脑桥髓鞘溶解症，且无瞳孔变化或痉挛性四肢轻瘫等典型神经学表现。幻觉和人格改变是诊断的线索，应被视为脑桥髓鞘溶解症的非典型表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ffb/11206230/118e065cecc1/1980-5764-DN-18-e20230068-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ffb/11206230/118e065cecc1/1980-5764-DN-18-e20230068-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ffb/11206230/118e065cecc1/1980-5764-DN-18-e20230068-gf01.jpg

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本文引用的文献

1
Central pontine (and extrapontine) myelinolysis despite appropriate sodium correction.
Pract Neurol. 2020 Feb;20(1):64-65. doi: 10.1136/practneurol-2019-002347. Epub 2019 Aug 29.
2
Acute Psychosis as Main Manifestation of Central Pontine Myelinolysis.以急性精神病为主要表现的桥脑中央髓鞘溶解症
Case Rep Neurol Med. 2017;2017:1471096. doi: 10.1155/2017/1471096. Epub 2017 Mar 14.
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Acute psychosis with a favorable outcome as a complication of central pontine/extrapontine myelinolysis in a middle aged man.
J Midlife Health. 2012 Jul;3(2):103-5. doi: 10.4103/0976-7800.104475.
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Peduncular hallucinosis secondary to central pontine myelinolysis.纹状体性幻觉继发于脑桥中央髓鞘溶解症。
Psychiatry Clin Neurosci. 2012 Dec;66(7):618-21. doi: 10.1111/j.1440-1819.2012.02399.x.
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Clinical and radiologic correlations of central pontine myelinolysis syndrome.脑桥中央髓鞘溶解症的临床与影像学相关性。
Mayo Clin Proc. 2011 Nov;86(11):1063-7. doi: 10.4065/mcp.2011.0239. Epub 2011 Oct 13.
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A trident in the brain, central pontine myelinolysis.大脑中的三叉戟，即中央桥脑髓鞘溶解症。
Pract Neurol. 2009 Aug;9(4):231-2. doi: 10.1136/jnnp.2009.182469.
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Catatonic syndrome in central pontine/extrapontine myelinolysis: a case report.中央脑桥/脑桥外髓鞘溶解症中的紧张症综合征：一例报告
Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1344-6. doi: 10.1016/j.pnpbp.2008.03.009. Epub 2008 Mar 20.
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Psychotic disorder in a patient with central and extrapontine myelinolysis.
Psychiatry Clin Neurosci. 2007 Jun;61(3):320-2. doi: 10.1111/j.1440-1819.2007.01648.x.
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J Neurol Neurosurg Psychiatry. 2004 Sep;75 Suppl 3(Suppl 3):iii22-8. doi: 10.1136/jnnp.2004.045906.
10
Central pontine myelinolysis: a hitherto undescribed disease occurring in alcoholic and malnourished patients.中央pontine髓鞘溶解症：一种迄今未被描述的疾病，发生于酗酒和营养不良的患者。
AMA Arch Neurol Psychiatry. 1959 Feb;81(2):154-72.