Cole W H, Humphrey L
Ann Surg. 1985 Jul;202(1):9-20. doi: 10.1097/00000658-198507000-00002.
Although surgery, radiology, and anticancer chemicals have been effective in the treatment of cancer, the immunologic phase of therapy deserves more effort and thought, because the possibilities are considerable. However, the immunologic phase is so complicated that, without the advances made during the past few years, little could be expected from immunology. The focus of this paper is on the immunosuppression produced by major cancer operations, at which time the patient needs immunologic help.
虽然手术、放射学和抗癌化学药物在癌症治疗中已卓有成效,但免疫治疗阶段仍值得付出更多努力并深入思考,因为其潜力巨大。然而,免疫治疗阶段极为复杂,若没有过去几年所取得的进展,免疫学很难有大的作为。本文重点关注大型癌症手术所产生的免疫抑制,而此时患者恰恰需要免疫方面的帮助。