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超速起搏和利多卡因对人体房室交界区心律的影响:异常自律性的作用。

The effects of overdrive pacing and lidocaine on atrioventricular junctional rhythm in man: the role of abnormal automaticity.

作者信息

Tenczer J, Littmann L, Rohla M, Fenyvesi T

出版信息

Circulation. 1985 Sep;72(3):480-6. doi: 10.1161/01.cir.72.3.480.

DOI:10.1161/01.cir.72.3.480
PMID:3893791
Abstract

The effects of overdrive pacing and lidocaine were studied in 22 patients with atrioventricular (AV) junctional rhythms. Based on the responses to cardiac pacing and lidocaine, patients were divided into two groups. AV junctional rhythms in group I (17 patients) were suppressed by overdrive pacing, and their rates were decreased by lidocaine. Lidocaine also prolonged the junctional recovery time in these patients. AV junctional rhythms in group II (five patients) were not suppressed by overdrive pacing. In contrast, the rate increased after overdrive pacing. Lidocaine did not alter the basic cycle lengths or the recovery times of the AV junctional rhythms in this group of patients. The data suggest that AV junctional rhythms in group I were caused by normal automaticity, while those in group II were probably due to abnormal automaticity.

摘要

对22例房室交界区心律患者进行了超速起搏和利多卡因的效应研究。根据对心脏起搏和利多卡因的反应,将患者分为两组。第一组(17例患者)的房室交界区心律可被超速起搏抑制,其心率可被利多卡因降低。利多卡因还延长了这些患者的交界区恢复时间。第二组(5例患者)的房室交界区心律不能被超速起搏抑制。相反,超速起搏后心率增加。利多卡因对该组患者的房室交界区心律的基本周期长度或恢复时间没有影响。数据表明,第一组的房室交界区心律由正常自律性引起,而第二组的可能是由异常自律性所致。

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