Bekka Elias, Christen Samuel E, Hermann Laura, Exadaktylos Aristomenis K, Haschke Manuel, Liakoni Evangelia
Clinical Pharmacology and Toxicology, Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Graduate School for Health Sciences, University of Bern, Bern, Switzerland.
Int J Anal Chem. 2024 Jun 10;2024:4400606. doi: 10.1155/2024/4400606. eCollection 2024.
In case of suspected acute recreational drug toxicity, immunoassays are commonly used as diagnostic tools. Although easy to handle, understanding of their limitations is necessary for a correct interpretation of the results. The aim of this project was to investigate residents' knowledge regarding drug screening immunoassays at a Swiss hospital group.
All residents of a large hospital group in Switzerland were invited by e-mail to participate in an anonymous survey. Following ten multiple choice questions on drug screening tests, the participants were also asked about their demographics, whether they used drug screening tests on a regular basis, and how confident they felt in their ability to interpret test results.
The ten knowledge questions were answered by 110 of the 1026 residents (11%). Among the 108 participants with available demographics, 90% were 25-35 years old, 63% were female, and 70% were at least in their 4 year of residency. The median score of correct answers was 4 out of 10 (range 0-7) and in 50% of the questions, the correct answer was the most frequently selected response. No significant differences in the knowledge scores were found based on the training, confidence level, or the frequency of drug tests used in daily work.
This survey revealed widespread knowledge gaps among residents regarding the interpretation of immunoassay-based drug test results. These findings can be used to implement educational measures on this topic and might provide a basis for targeted information on common pitfalls to be included in laboratory reports.
在怀疑急性娱乐性药物中毒的情况下，免疫测定法通常用作诊断工具。尽管操作简便，但为了正确解读结果，了解其局限性是必要的。本项目的目的是调查瑞士一家医院集团的住院医师对药物筛查免疫测定法的了解情况。
通过电子邮件邀请瑞士一家大型医院集团的所有住院医师参与一项匿名调查。在关于药物筛查测试的十个多项选择题之后，还询问了参与者的人口统计学信息、是否定期使用药物筛查测试以及他们对自己解读测试结果能力的信心程度。
1026名住院医师中的110名（11%）回答了这十个知识问题。在提供了人口统计学信息的108名参与者中，90%的年龄在25至35岁之间，63%为女性，70%至少处于住院医师培训的第四年。正确答案的中位数得分是10分中的4分（范围为0至7分），在50%的问题中，正确答案是被选频率最高的选项。基于培训、信心水平或日常工作中使用药物检测的频率，未发现知识得分有显著差异。
这项调查揭示了住院医师在基于免疫测定法的药物检测结果解读方面存在广泛的知识空白。这些发现可用于实施关于该主题的教育措施，并可能为实验室报告中纳入常见陷阱的针对性信息提供依据。
