• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Precision Medicine for All?: What About Hypertrophic Cardiomyopathy?

作者信息

Maron Barry J, Maron Martin S, Rowin Ethan J

机构信息

HCM Center, Lahey Hospital & Medical Center, Burlington, Massachusetts, USA.

出版信息

JACC Adv. 2024 Apr 9;3(5):100922. doi: 10.1016/j.jacadv.2024.100922. eCollection 2024 May.

DOI:10.1016/j.jacadv.2024.100922
PMID:38939636
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11198136/
Abstract
摘要

相似文献

1
Precision Medicine for All?: What About Hypertrophic Cardiomyopathy?全民精准医疗？那肥厚型心肌病呢？
JACC Adv. 2024 Apr 9;3(5):100922. doi: 10.1016/j.jacadv.2024.100922. eCollection 2024 May.
2
Coexistence of sudden cardiac death and end-stage heart failure in familial hypertrophic cardiomyopathy.家族性肥厚型心肌病中心脏性猝死与终末期心力衰竭的共存
J Am Coll Cardiol. 1993 Aug;22(2):489-97. doi: 10.1016/0735-1097(93)90054-5.
3
Hypertrophic Cardiomyopathy as a Cause of Sudden Cardiac Death in the Young: A Meta-Analysis.肥厚型心肌病作为年轻人心脏性猝死的原因：一项荟萃分析。
Am J Med. 2016 May;129(5):486-496.e2. doi: 10.1016/j.amjmed.2015.12.027. Epub 2016 Jan 20.
4
Screening for hypertrophic cardiomyopathy in young athletes.年轻运动员肥厚型心肌病的筛查。
N Engl J Med. 1998 Aug 6;339(6):364-9. doi: 10.1056/NEJM199808063390602.
5
Association of Race With Disease Expression and Clinical Outcomes Among Patients With Hypertrophic Cardiomyopathy.种族与肥厚型心肌病患者疾病表现和临床结局的相关性。
JAMA Cardiol. 2020 Jan 1;5(1):83-91. doi: 10.1001/jamacardio.2019.4638.
6
[Sudden death during Holter electrocardiographic monitoring in a patient with hypertrophic cardiomyopathy].
J Cardiol. 1998 May;31(5):297-303.
7
Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy.肥厚型心肌病中左心室流出道梗阻对临床结局的影响。
N Engl J Med. 2003 Jan 23;348(4):295-303. doi: 10.1056/NEJMoa021332.
8
Genotype-positive status in patients with hypertrophic cardiomyopathy is associated with higher rates of heart failure events.肥厚型心肌病患者的基因型阳性状态与更高的心力衰竭事件发生率相关。
Circ Cardiovasc Genet. 2014 Aug;7(4):416-22. doi: 10.1161/CIRCGENETICS.113.000331. Epub 2014 Jun 8.
9
[Sudden death (V). Identification and treatment of patients with hypertrophic cardiomyopathy at risk of sudden death].[猝死（五）。肥厚型心肌病猝死风险患者的识别与治疗]
Rev Esp Cardiol. 2000 Jan;53(1):123-30. doi: 10.1016/s0300-8932(00)75069-x.
10
Impact of type 2 diabetes mellitus on mid-term mortality for hypertrophic cardiomyopathy patients who underwent septal myectomy.2 型糖尿病对接受室间隔心肌切除术的肥厚型心肌病患者中期死亡率的影响。
Cardiovasc Diabetol. 2020 May 13;19(1):64. doi: 10.1186/s12933-020-01036-1.

本文引用的文献

1
An Ethical and Financial Obligation for Sickle Cell Disease Gene Therapy in the United States.美国镰状细胞病基因治疗的伦理与财务义务
Ann Intern Med. 2024 Jan;177(1):85-86. doi: 10.7326/M23-2428. Epub 2023 Dec 5.
2
Gene Therapy in Cardiology: Is a Cure for Hypertrophic Cardiomyopathy on the Horizon?心脏病学中的基因治疗：肥厚型心肌病的治疗方法是否即将出现？
Can J Cardiol. 2024 May;40(5):777-788. doi: 10.1016/j.cjca.2023.11.024. Epub 2023 Nov 25.
3
Efficient in vivo genome editing prevents hypertrophic cardiomyopathy in mice.高效的体内基因组编辑可预防小鼠肥厚型心肌病。
Nat Med. 2023 Feb;29(2):412-421. doi: 10.1038/s41591-022-02190-7. Epub 2023 Feb 16.
4
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.马卡丹特治疗有症状梗阻性肥厚型心肌病（EXPLORER-HCM）的随机、双盲、安慰剂对照、3 期临床试验
Lancet. 2020 Sep 12;396(10253):759-769. doi: 10.1016/S0140-6736(20)31792-X. Epub 2020 Aug 29.
5
Hypertrophic Cardiomyopathy: Is a 'Cure' Coming . . . Or Is It Already Here?肥厚型心肌病：“治愈方法”即将到来……还是已经出现了？
Am J Med. 2020 Aug;133(8):886-888. doi: 10.1016/j.amjmed.2020.03.015.
6
Clinical Course and Management of Hypertrophic Cardiomyopathy.肥厚型心肌病的临床病程与管理
N Engl J Med. 2018 Aug 16;379(7):655-668. doi: 10.1056/NEJMra1710575.
7
Correction of a pathogenic gene mutation in human embryos.人类胚胎中致病基因突变的纠正。
Nature. 2017 Aug 24;548(7668):413-419. doi: 10.1038/nature23305. Epub 2017 Aug 2.
8
How Hypertrophic Cardiomyopathy Became a Contemporary Treatable Genetic Disease With Low Mortality: Shaped by 50 Years of Clinical Research and Practice.肥厚型心肌病如何成为一种当代可治疗、低死亡率的遗传性疾病：50 年临床研究与实践的塑造。
JAMA Cardiol. 2016 Apr 1;1(1):98-105. doi: 10.1001/jamacardio.2015.0354.