University Hospital Leipzig, Leipzig, Germany.
Int Ophthalmol. 2024 Jun 28;44(1):293. doi: 10.1007/s10792-024-03205-7.
This prospective clinical study evaluates the effect of a silicone stent tube (SST) on the success rate of endonasal-endoscopic dacryocystorhinostomy (EN-DCR) to treat primary acquired nasolacrimal duct obstruction.
Patients were randomly assigned to receive EN-DCR with or without SST intubation over a period of 3 months. The surgery was performed using standardized techniques. Patients were assessed at three different timepoints: one day, 12 weeks and 24 weeks after the surgery. The results were compared in order to evaluate statistical differences. Surgical success was determined by means of positive irrigation procedures, as well as by the improvement of symptoms and a high level of patient satisfaction.
A total of 56 randomized cases completed 24 weeks of follow up. 1 Patient dropped out due to malignant genesis of the nasolacrimal duct obstruction. After 24 weeks of follow up no statistically significant differences in levels of epiphora (p > .10) or patency (p > .16) were revealed. Comparisons regarding changes in time did not show levels of significance (p > .28).
This study could not confirm a statistically significant benefit or disadvantage for SST Insertion in EN-DCR.
本前瞻性临床研究评估了硅胶支架管（SST）对内鼻内镜下鼻腔泪囊吻合术（EN-DCR）治疗原发性获得性鼻泪管阻塞成功率的影响。
患者在 3 个月内随机分配接受 EN-DCR 联合或不联合 SST 插管。手术采用标准化技术进行。患者在术后 1 天、12 周和 24 周进行评估。比较结果以评估统计学差异。手术成功通过积极的冲洗程序、症状改善和高患者满意度来确定。
共 56 例随机病例完成了 24 周的随访。1 例患者因鼻泪管阻塞的恶性病因而退出。24 周随访后，溢泪（p>.10）或通畅（p>.16）水平无统计学差异。关于时间变化的比较没有显示出显著水平（p>.28）。
本研究不能证实 SST 插入 EN-DCR 对内鼻内镜下鼻腔泪囊吻合术的成功率有统计学上的显著优势或劣势。
