Department of Surgical Oncology, University of Pittsburgh, 3471 Fifth Avenue, Kaufmann Suite 101, Pittsburgh, PA 15213, USA.
Department of Surgical Oncology, University of Pittsburgh, 3471 Fifth Avenue, Kaufmann Suite 101, Pittsburgh, PA 15213, USA.
Surg Clin North Am. 2024 Aug;104(4):791-798. doi: 10.1016/j.suc.2024.02.008. Epub 2024 Apr 2.
Primary hyperparathyroidism (PHPT) is a disorder characterized by the autonomous overproduction of parathyroid hormone (PTH) that leads to hypercalcemia, multiple clinical sequelae, and heterogenous presentation. Whether PHPT is caused by a single benign adenoma (85%), multiglandular disease (15%), or parathyroid carcinoma (1%), surgery is the definitive treatment.
原发性甲状旁腺功能亢进症(PHPT)是一种以甲状旁腺激素(PTH)自主过度分泌为特征的疾病,可导致高钙血症、多种临床后遗症和异质性表现。无论 PHPT 是由单个良性腺瘤(85%)、多腺体疾病(15%)还是甲状旁腺癌(1%)引起,手术都是明确的治疗方法。