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从冷冻到喂养:一家四级学术性新生儿重症监护病房中储存的捐赠人乳的储存特性

From frozen to feeding: storage characteristics of banked donor human milk used in a single level IV academic neonatal intensive care unit.

作者信息

Chetta Katherine, Galemmo Mary, Camilon Terence, Tiernan Wrenn, Savino Whitney, Rohrer Allison, Baatz John, Wagner Carol

机构信息

Medical University of South Carolina.

Medical Univ South Carolina.

出版信息

Res Sq. 2024 Jun 13:rs.3.rs-4486977. doi: 10.21203/rs.3.rs-4486977/v1.

Abstract

BACKGROUND

The storage time of banked donor human milk (DHM) administered in an academic hospital to critically ill preterm neonates was previously unknown.

OBJECTIVE

This study was designed to determine the storage time of banked DHM by measurements obtained at the hospital level (by lot finish date) and individual patient level (by feeding date) over 2-year observation period.

RESULTS

Both methods of measuring storage time (hospital-level and patient-level) showed that DHM was stored on average 8 ±1 months before use. Variations in storage time fluctuated across months with a minimum and maximum storage duration of 119 to 317 days. Most infants received a median of 3 [2-5 IQR] unique lots of DHM.

CONCLUSION

The storage time of DHM was successfully measured. Over 95% of DHM received was stored longer than 6 months. Storage times varied widely, uncovering a potential area of future research.

摘要

背景

此前,在一家学术医院中,用于救治危重新生儿的捐赠人乳(DHM)的储存时间尚不清楚。

目的

本研究旨在通过在两年观察期内,在医院层面(按批次截止日期)和个体患者层面(按喂养日期)进行测量,来确定储存的DHM的储存时间。

结果

两种测量储存时间的方法(医院层面和患者层面)均显示,DHM在使用前平均储存了8±1个月。储存时间的变化随月份波动,最短和最长储存时长分别为119至317天。大多数婴儿接受的DHM批次中位数为3[2-5四分位距]。

结论

成功测量了DHM的储存时间。超过95%的接收的DHM储存时间超过6个月。储存时间差异很大,揭示了一个未来研究的潜在领域。

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