Doshi Nikhil I, Khillare Kishor M, Vaishnav Bhumika, Pailla Ruchitha, Shaha Suvidha
General Medicine, Dr. D. Y. Patil Medical College, Hospital & Research Centre, Pune, IND.
Psychology, Ajeenkya DY Patil School Of Engineering, Pune, IND.
Cureus. 2024 May 31;16(5):e61416. doi: 10.7759/cureus.61416. eCollection 2024 May.
Rodenticides are easily available in the market and suicidal attempts by ingesting such poisonous products are commonly reported in rural India. We aimed to analyze predictive factors, biological markers, and treatment outcomes among patients who ingested rodenticides (yellow phosphorus) with the brand name, Rattol. Here, we present three such cases who were admitted to a tertiary care hospital. We recorded socio-demographic characteristics, probable predictive factors, and serial charting biological markers. Conventional treatment was given to these cases. All cases were young women (age range: 17-30 years) from rural areas, two were married and one was unmarried. The approximate quantity of ingestion was 20, 10, and 5 grams, respectively. The time lag between the ingestion and sought first health care was 6 hours, 18 hours, and 1 hour, respectively. Major symptoms were vomiting, abdominal pain, and headache. Biological markers, including total bilirubin, alanine aminotransferase, aspartate aminotransferase, creatinine, prothrombin time, international normalized ratio, and model for end-stage liver disease (MELD) score were statistically significant. Two women had toxic hepatitis and acute liver failure and one did not have any organ damage. All of them were recovered within 17 days of mean hospital stay. A lethal dosage of rodenticides and delayed presentation to the hospital can prompt acute liver failure and severe ailment. Creating awareness, promoting mental health and suicide prevention, and framing proper guidelines for treatment will reduce morbidity and mortality.
灭鼠药在市场上很容易买到,在印度农村地区,吞食此类有毒产品的自杀企图屡见不鲜。我们旨在分析吞食名为“Rattol”的灭鼠药(黄磷)的患者的预测因素、生物标志物和治疗结果。在此,我们介绍三例入住三级护理医院的此类病例。我们记录了社会人口学特征、可能的预测因素以及连续记录生物标志物。对这些病例进行了常规治疗。所有病例均为来自农村地区的年轻女性(年龄范围:17 - 30岁),其中两名已婚,一名未婚。吞食的大致数量分别为20克、10克和5克。吞食与首次寻求医疗护理之间的时间间隔分别为6小时、18小时和1小时。主要症状为呕吐、腹痛和头痛。包括总胆红素、丙氨酸转氨酶、天冬氨酸转氨酶、肌酐、凝血酶原时间、国际标准化比值和终末期肝病模型(MELD)评分在内的生物标志物具有统计学意义。两名女性患有中毒性肝炎和急性肝衰竭,一名没有任何器官损伤。她们在平均住院17天内均康复。灭鼠药的致死剂量和延迟就医会引发急性肝衰竭和严重疾病。提高认识、促进心理健康和预防自杀以及制定适当的治疗指南将降低发病率和死亡率。