Tantia Parav, Kadam Abhinav, Yadav Jagrati, Acharya Sourya, Kumar Sunil
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, IND.
Department of Medical Oncology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, IND.
Cureus. 2024 May 31;16(5):e61421. doi: 10.7759/cureus.61421. eCollection 2024 May.
Gastric cancer is the fifth leading cause of cancer-related deaths in the world. The occurrence of bone metastases (BM) in gastric cancer without prior gastrointestinal (GI) symptoms is a rare phenomenon that has been sporadically documented in the existing literature. We report a case of a 27-year-old male presenting with chief complaints of severe backache for one month. After an upper gastrointestinal endoscopy and biopsy, the primary source of cancer was identified as a solitary gastric adenocarcinoma, supporting the diagnosis of bony metastases on the magnetic resonance imaging (MRI) of the spine. The patient was planned to start on palliative chemotherapy (5-fluorouracil, leucovorin, oxaliplatin, and docetaxel {FLOT} regimen) with palliative radiotherapy of 20 Gy in five fractions to bony metastasis. The patient denied treatment and was discharged against medical advice.
胃癌是全球癌症相关死亡的第五大主要原因。在没有先前胃肠道（GI）症状的胃癌中发生骨转移（BM）是一种罕见现象，现有文献中仅有零星记载。我们报告一例27岁男性病例，主要主诉为严重背痛1个月。经过上消化道内镜检查和活检，确定癌症的原发部位为孤立性胃腺癌，脊柱磁共振成像（MRI）支持骨转移的诊断。计划让该患者开始姑息化疗（5-氟尿嘧啶、亚叶酸钙、奥沙利铂和多西他赛{FLOT}方案），并对骨转移灶进行20 Gy分五次的姑息性放疗。患者拒绝治疗，不听从医嘱出院。
