Barkander Anna, Nolan Andrew S, Jóhannesson Gauti, Economou Mario A
Department of Clinical Sciences, Ophthalmology, Umeå University, Umeå, Sweden.
Department of Ophthalmology, Östersund Hospital, Östersund, Sweden.
Clin Ophthalmol. 2024 Jun 24;18:1811-1817. doi: 10.2147/OPTH.S468809. eCollection 2024.
To investigate the influence of laser trabeculoplasty (LTP) on subsequent surgery with combined phacoemulsification/Kahook Dual Blade goniotomy (phaco-KDB) in patients with open-angle glaucoma or intraocular hypertension.
Patients undergoing phaco-KDB between 2019 and 2021 were divided into previously LTP treated and previously non-LTP treated, and LTP-treatment included argon laser trabeculoplasty (ALT) and selective laser trabeculoplasty (SLT). The primary goal was to investigate if previous LTP influenced later surgical outcome of phaco-KDB. The secondary goal was to investigate if the outcome of LTP could be predictive of the outcome of subsequent phaco-KDB. We also compared IOP- and medication reductions between LTP and non-LTP treated patients.
A total of 111 LTP treated patients were compared to 139 non-LTP treated patients. In LTP treated patients, surgical success of phaco-KDB was 82.9%, compared to 88.5% in non-LTP treated patients (P=0.20). Reductions in IOP and medications were similar between groups. Furthermore, within the LTP group, patients with successful LTP-treatment had a subsequent surgical success of phaco-KDB in 80.7%, compared to 83.0% in patients with unsuccessful LTP-treatment (P=0.765).
Previous LTP treatment does not predict the outcome of phaco-KDB. Furthermore, no correlation was found between the LTP effect and a later surgical success of phaco-KDB.
探讨激光小梁成形术（LTP）对开角型青光眼或高眼压症患者后续行白内障超声乳化吸除联合卡胡克双刃小梁切开术（phaco-KDB）手术的影响。
将2019年至2021年间接受phaco-KDB手术的患者分为曾接受LTP治疗组和未接受LTP治疗组，LTP治疗包括氩激光小梁成形术（ALT）和选择性激光小梁成形术（SLT）。主要目的是研究既往LTP治疗是否会影响phaco-KDB手术的后期效果。次要目的是研究LTP的效果是否可预测后续phaco-KDB手术的效果。我们还比较了LTP治疗组和未接受LTP治疗组患者眼压降低情况及用药减少情况。
共111例接受LTP治疗的患者与139例未接受LTP治疗的患者进行了比较。接受LTP治疗的患者中，phaco-KDB手术成功率为82.9%，未接受LTP治疗的患者中手术成功率为88.5%（P=0.20）。两组间眼压降低及用药减少情况相似。此外，在LTP治疗组中，LTP治疗成功的患者后续phaco-KDB手术成功率为80.7%，LTP治疗失败的患者中手术成功率为83.0%（P=0.765）。
既往LTP治疗不能预测phaco-KDB手术的效果。此外，未发现LTP的效果与后续phaco-KDB手术成功之间存在相关性。
