Peng Yao-Nan, Liu Zhen-Zhen, Qiao Liang
Department of Neurosurgery, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Department of Rehabilitation Medicine, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
J Craniofac Surg. 2024 Jul 1. doi: 10.1097/SCS.0000000000010432.
To compare the clinical application effect and safety of polyetheretherketone (PEEK) and titanium mesh (TM) in cranioplasty.
Four-year retrospective comparison of patients (96 cases) undergoing synthetic cranioplasty with PEEK or TM. The patients were divided into the PEEK group (24 cases) and the TM group (72 cases) according to the implants, and the patient demographics, general conditions before the operation, postoperative complications, length of postoperative hospital stay, total costs, satisfaction with shaping and long-term complications were compared between the 2 groups.
Patients in the PEEK group were younger than those in the TM group (P=0.019). Hospitalization costs were significantly higher in the PEEK group than in the TM group (P<0.001). The incidence of postoperative subcutaneous effusion was 33% in the PEEK group and 6.9% in the TM group, which suggests that patients in the PEEK group had a higher risk of postoperative subcutaneous effusion (P=0.001). There was no significant difference in the incidence of long-term complications and cosmetic satisfaction between the 2 groups at 4 years postoperatively.
In this study, both titanium mesh and PEEK are reliable implants for cranioplasty. Titanium mesh is widely used in cranioplasty due to its cost-effective performance. PEEK has gradually gained recognition due to the characteristics of the material and surgical procedure, but the price needs to be further reduced, and attention should be paid to the occurrence and treatment of early postoperative subcutaneous effusion.
比较聚醚醚酮(PEEK)和钛网(TM)在颅骨成形术中的临床应用效果及安全性。
对接受PEEK或TM人工颅骨成形术的患者(96例)进行为期四年的回顾性比较。根据植入物将患者分为PEEK组(24例)和TM组(72例),比较两组患者的人口统计学资料、术前一般情况、术后并发症、术后住院时间、总费用、塑形满意度及远期并发症。
PEEK组患者比TM组患者年轻(P = 0.019)。PEEK组的住院费用显著高于TM组(P < 0.001)。PEEK组术后皮下积液发生率为33%,TM组为6.9%,提示PEEK组患者术后皮下积液风险更高(P = 0.001)。术后4年,两组远期并发症发生率及美容满意度差异无统计学意义。
在本研究中,钛网和PEEK都是颅骨成形术可靠的植入物。钛网因其性价比高而广泛应用于颅骨成形术。PEEK由于材料特性和手术操作特点逐渐得到认可,但价格有待进一步降低,且应关注术后早期皮下积液的发生及处理。