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PEEK 与钛颅骨修补重建患者的手术和患者报告结果。

Surgical and Patient-Reported Outcomes in Patients With PEEK Versus Titanium Cranioplasty Reconstruction.

机构信息

Division of Plastic Surgery, Mayo Clinic.

Mayo Clinic Alix School of Medicine, Mayo Clinic.

出版信息

J Craniofac Surg. 2021;32(1):193-197. doi: 10.1097/SCS.0000000000007192.

Abstract

BACKGROUND

Several materials are available for cranioplasty reconstruction and consensus regarding the ideal material is lacking. The goal of this study is to present surgical and patient-reported outcomes with PEEK versus Titanium alloplastic cranioplasty.

METHODS

A retrospective review of all patients who underwent alloplastic cranioplasty with PEEK or Titanium from 2010 to 2017 was conducted. Patient demographics and complications were abstracted and analyzed. Information regarding patient-reported outcomes was collected through a telephone survey.

RESULTS

A total of 72 patients (median age 55 years) who underwent 77 cranioplasties were identified (38% PEEK, n = 29; 62% Titanium, n = 48). Overall complication rates were similar between the PEEK (24%, n = 7) and Titanium groups (23%, n = 11), P = 0.902. Similarly, implant failure was similar between the 2 groups (7% in PEEK (n = 2), 13% in Titanium (n = 6), P = 0.703). History of radiation was associated with increased rate of infection in patients with Titanium mesh cranioplasty (38% in radiated patients (n = 3), 3% in nonradiated patients (n = 1), P = 0.012) but not PEEK implants (0% infection rate in radiated patients (n = 0), 15% in nonradiated patients (n = 4), P = 1.000). A total of 24 patients (33% response rate) participated in the telephone survey. All PEEK cranioplasty patients who responded to our survey (n = 13) reported good to excellent satisfaction, while 72% of our titanium mesh cohort (n = 8) described good or excellent satisfaction and 27% (n = 3) reported acceptable result.

CONCLUSION

Cranial reconstruction is associated with high satisfaction among cranioplasty patients with PEEK or Titanium showing comparable complications, failure, and patient-reported satisfaction rates. Patients with history of radiotherapy demonstrated a higher infection rate when titanium mesh was used.

摘要

背景

有多种材料可用于颅骨修复重建,但对于理想材料尚未达成共识。本研究旨在比较聚醚醚酮(PEEK)与钛合金两种颅骨修复材料的手术效果和患者报告结局。

方法

回顾性分析了 2010 年至 2017 年间采用 PEEK 或钛合金行颅骨修复术的所有患者。提取并分析患者的人口统计学数据和并发症。通过电话调查收集患者报告结局相关信息。

结果

共纳入 72 例(中位年龄 55 岁)患者,共 77 例颅骨修复术,其中 38%(29 例)采用 PEEK,62%(48 例)采用钛合金。PEEK 组(24%,7 例)和钛合金组(23%,11 例)的总体并发症发生率相似,P=0.902。同样,两组的植入物失败率也相似(PEEK 组为 7%[2 例],钛合金组为 13%[6 例],P=0.703)。钛合金颅骨修复患者中,有放疗史者感染率较高(放疗患者为 38%[3 例],无放疗患者为 3%[1 例],P=0.012),而 PEEK 植入物无此差异(放疗患者为 0%[0 例],无放疗患者为 15%[4 例],P=1.000)。共有 24 例患者(33%的应答率)参与了电话调查。接受调查的所有 PEEK 颅骨修复患者(n=13)报告满意度良好至优秀,而钛合金组(n=8)中 72%报告良好至优秀,27%(n=3)报告满意度尚可。

结论

PEEK 或钛合金颅骨修复重建后患者满意度较高,并发症、失败率和患者报告结局相似。使用钛网时,有放疗史的患者感染率较高。

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