Usmani Sharjeel, Jain Anjali, Al Riyami Khulood, Niaz Zahida, Kheruka Subhash, Jayakrishnan Vipin V
Sultan Qaboos Comprehensive Cancer Care and Research Center, Department of Radiology and Nuclear Medicine, Muscat, Oman.
Sultan Qaboos Comprehensive Cancer Care and Research Center, Department of Pathology, Muscat, Oman.
Mol Imaging Radionucl Ther. 2024 Jun 28;33(2):106-108. doi: 10.4274/mirt.galenos.2023.58224.
Tc-99m methylene diphosphonate (MDP) is a bone imaging agent used for skeletal staging, but it can also be localized in extraosseous calcifying lesions. We report a case of an 84-year-old woman with breast carcinoma who underwent surgery followed by radiotherapy 10 years ago and now presented with a right axillary mass referred for Tc-99m MDP to exclude bone metastasis. Tc-99m MDP shows intense tracer uptake in the right thoracic region corresponding to the site of calcified soft tissue mass in the right lateral chest wall. Subsequent ultrasonography revealed an ill-defined lesion containing coarse calcifications. Biopsy showed radiation-induced sarcoma. Extra osseous Tc-99m MDP uptake may provide important diagnostic information that may alter patient management.
锝-99m亚甲基二膦酸盐（MDP）是一种用于骨骼分期的骨显像剂，但它也可定位于骨外钙化病变。我们报告一例84岁乳腺癌女性病例，该患者10年前接受了手术及放疗，现出现右腋窝肿块，转诊接受锝-99m MDP检查以排除骨转移。锝-99m MDP显示右侧胸部区域有强烈的示踪剂摄取，对应于右侧胸壁钙化软组织肿块的部位。随后的超声检查发现一个边界不清的病变，内有粗大钙化。活检显示为放射性肉瘤。骨外锝-99m MDP摄取可能提供重要的诊断信息，从而改变患者的治疗方案。
