National Center for Respiratory Medicine, State Key Laboratory of Respiratory Health and Multimorbidity, National Clinical Research Center for Respiratory Diseases, Institute of Respiratory Medicine, Chinese Academy of Medical Sciences, Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Beijing, China.
Department of Pulmonary and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Respiration. 2024;103(9):583-586. doi: 10.1159/000539974. Epub 2024 Jun 27.
Subglottic stenosis, manifested by granulation tissue hyperplasia, is challenging and requires multiple repeated treatments and stent maintenance at times. Corticosteroids prevent severe subglottic stenosis development owing to their antifibrotic and anti-inflammatory properties. Submucosal injection of glucocorticoids, a useful adjuvant therapeutic method, improves the mean interval between endoscopic procedures and reduces airway restenosis risks.
We report a rare case of a man with complex subglottic stenosis who underwent balloon dilatation combined with cryotherapy, stent placement, and adjuvant submucosal triamcinolone injection. The drug was injected efficiently and safely into the submucosal layer under percutaneous ultrasound guidance, and subglottic stenosis was well-controlled at a low cost.
POCUS-guided medication injections may be a useful adjuvant medical therapy for subglottic stenosis.
声门下狭窄表现为肉芽组织增生,具有挑战性,有时需要多次重复治疗和支架维护。皮质类固醇因其抗纤维化和抗炎特性可预防严重的声门下狭窄发展。黏膜下注射糖皮质激素是一种有用的辅助治疗方法,可延长内镜操作之间的平均间隔时间,并降低气道再狭窄的风险。
我们报告了一例罕见的复杂性声门下狭窄男性患者,他接受了球囊扩张联合冷冻疗法、支架置入和辅助黏膜下曲安奈德注射。在经皮超声引导下,药物可有效且安全地注入黏膜下层,且声门下狭窄得到了很好的控制,费用较低。
POCUS 引导下的药物注射可能是声门下狭窄的一种有用的辅助治疗方法。