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一项针对成人脊柱畸形手术方法的比较队列研究,随访时间至少为2年。

A comparative cohort study of surgical approaches for adult spinal deformity at a minimum 2-year follow-up.

作者信息

Kazarian Gregory S, Feuchtbaum Eric, Bao Hongda, Soroceanu Alex, Kelly Michael P, Kebaish Khaled M, Shaffrey Christopher I, Burton Douglas C, Ames Christopher P, Mundis Gregory M, Bess Shay, Klineberg Eric O, Swamy Ganesh, Schwab Frank J, Kim Han Jo

机构信息

Department of Orthopaedic Surgery, Hospital for Special Surgery, 535 E 70th St, New York, NY, 10021, USA.

Orthopaedic Surgery, University of Calgary, Calgary, Canada.

出版信息

Eur Spine J. 2024 Jul 2. doi: 10.1007/s00586-024-08354-y.

Abstract

STUDY DESIGN

This study was a retrospective multi-center comparative cohort study.

MATERIALS AND METHODS

A retrospective institutional database of operative adult spinal deformity patients was utilized. All fusions > 5 vertebral levels and including the sacrum/pelvis were eligible for inclusion. Revisions, 3 column osteotomies, and patients with < 2-year clinical follow-up were excluded. Patients were separated into 3 groups based on surgical approach: 1) posterior spinal fusion without interbody (PSF), 2) PSF with interbody (PSF-IB), and 3) anteroposterior (AP) fusion (anterior lumbar interbody fusion or lateral lumbar interbody fusion with posterior screw fixation). Intraoperative, radiographic, and clinical outcomes, as well as complications, were compared between groups with ANOVA and χ tests.

RESULTS

One-hundred and thirty-eight patients were included for study (PSF, n = 37; PSF-IB, n = 44; AP, n = 57). Intraoperatively, estimated blood loss was similar between groups (p = 0.171). However, the AP group had longer operative times (547.5 min) compared to PSF (385.1) and PSF-IB (370.7) (p < 0.001). Additionally, fusion length was shorter in PSF-IB (11.4) compared to AP (13.6) and PSF (12.9) (p = 0.004). There were no differences between the groups in terms of change in alignment from preoperative to 2 years postoperative. There were no differences in clinical outcomes. While postoperative complications were largely similar between groups, operative complications were higher in the AP group (31.6%) compared to the PSF (5.4%) and PSF-IB (9.1) groups (p < 0.001).

CONCLUSION

While there were differences in intraoperative outcomes (operative time and fusion length), there were no differences in postoperative clinical or radiographic outcomes. AP fusion was associated with a higher rate of operative complications.

摘要

研究设计

本研究为一项回顾性多中心比较队列研究。

材料与方法

利用一个关于接受手术治疗的成人脊柱畸形患者的回顾性机构数据库。所有融合超过5个椎体节段且包括骶骨/骨盆的病例均符合纳入标准。翻修手术、三柱截骨术以及临床随访时间不足2年的患者被排除。根据手术入路将患者分为3组:1)无椎间融合的后路脊柱融合术(PSF),2)有椎间融合的PSF(PSF-IB),3)前后路(AP)融合术(前路腰椎椎间融合术或侧路腰椎椎间融合术加后路螺钉固定)。采用方差分析和χ检验对组间的术中、影像学及临床结果以及并发症进行比较。

结果

共纳入138例患者进行研究(PSF组,n = 37;PSF-IB组,n = 44;AP组,n = 57)。术中,各组间估计失血量相似(p = 0.171)。然而,AP组的手术时间(547.5分钟)比PSF组(385.1分钟)和PSF-IB组(370.7分钟)更长(p < 0.001)。此外,PSF-IB组的融合长度(11.4)比AP组(13.6)和PSF组(12.9)更短(p = 0.004)。术前至术后2年的对线变化在各组间无差异。临床结果也无差异。虽然术后并发症在各组间大致相似,但AP组的手术并发症(31.6%)高于PSF组(5.4%)和PSF-IB组(9.1%)(p < 0.001)。

结论

虽然术中结果(手术时间和融合长度)存在差异,但术后临床及影像学结果无差异。AP融合术与更高的手术并发症发生率相关。

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