Hammer B
Wien Med Wochenschr. 1985 Jun 15;135(11):259-63.
The side effects associated with the use of Metrizamide, Iopamidol and Iotrol in two double blind studies on lumbar myelography were determined. The cause of headache is explained on the one hand as the result of the distribution of the contrast substance in the CSF space (early headache) and on the other hand due to the CSF leak through the puncture lesion. Iotrol seems to be the safest contrast substance for intrathecal use, however it should be used in the smallest possible amount to reduce even further contrast-related effects in myelography.
在两项关于腰椎脊髓造影的双盲研究中，确定了使用甲泛葡胺、碘帕醇和碘曲仑的副作用。头痛的原因一方面解释为造影剂在脑脊液空间中的分布（早期头痛），另一方面是由于脑脊液通过穿刺损伤漏出。碘曲仑似乎是鞘内使用最安全的造影剂，然而，应使用尽可能小的剂量，以进一步减少脊髓造影中与造影剂相关的影响。
