[Myelography and headache].

The side effects associated with the use of Metrizamide, Iopamidol and Iotrol in two double blind studies on lumbar myelography were determined. The cause of headache is explained on the one hand as the result of the distribution of the contrast substance in the CSF space (early headache) and on the other hand due to the CSF leak through the puncture lesion. Iotrol seems to be the safest contrast substance for intrathecal use, however it should be used in the smallest possible amount to reduce even further contrast-related effects in myelography.