Fine R N
Am J Kidney Dis. 1985 Aug;6(2):81-5. doi: 10.1016/s0272-6386(85)80145-1.
The adolescent with ESRD is frequently immature in relationship to chronological age. Growth and pubertal development are major concerns for the adolescent with ESRD. If renal failure had its onset prior to adolescence, it is likely that puberty will be delayed and ultimate adult height retarded for the patient requiring ESRD care during the adolescent period. Non-compliance with the therapeutic regimen is a major clinical problem encountered in the management of the adolescent. Significant morbidity can result from non-compliance with the dialysis regimen and non-compliance is a major cause of allograft loss in the adolescent transplant recipient. The special needs of the adolescent must be considered if ESRD care is to be successful.
患有终末期肾病（ESRD）的青少年在生理年龄方面往往不够成熟。生长和青春期发育是患有ESRD的青少年主要关心的问题。如果肾衰竭在青春期之前发病，那么对于在青春期需要接受ESRD治疗的患者来说，青春期很可能会延迟，最终成年身高也会受限。不遵守治疗方案是青少年治疗过程中遇到的一个主要临床问题。不遵守透析方案会导致严重的发病率，并且不遵守方案是青少年移植受者移植肾丧失的主要原因。如果要成功治疗ESRD，就必须考虑青少年的特殊需求。
