Baba E, Fukata T, Arakawa A
Am J Vet Res. 1985 Jul;46(7):1593-6.
To investigate a possible mechanism involved in the enhancement of Salmonella typhimurium infection in chickens concurrently infected with Eimeria tenella, S typhimurium was given orally to chickens 7 days after E tenella inoculation. The number of viable S typhimurium decreased in the ceca of chickens not inoculated with E tenella, whereas the number gradually increased in the ceca of chickens inoculated with E tenella. Cecal contents were analyzed for pH value, oxidation-reduction potential, and amounts of short-chain fatty acids and bile acids. In the ceca of E tenella-inoculated chickens, the oxidation-reduction potential significantly (P less than 0.05) shifted to the oxidative phase, and the concentration of volatile fatty acids (acetic acid, propionic acid, and butyric acid) significantly (P less than 0.05) decreased. In both aerobic and anaerobic incubations, the number of viable S typhimurium in vitro decreased as the molar concentration of fatty acids increased. Experimental evidence indicated that multiplication of S typhimurium in the ceca of E tenella-inoculated chickens was associated with decreased concentrations of volatile fatty acids.
为了研究在同时感染柔嫩艾美耳球虫的鸡中鼠伤寒沙门氏菌感染增强的可能机制，在接种柔嫩艾美耳球虫7天后给鸡口服鼠伤寒沙门氏菌。未接种柔嫩艾美耳球虫的鸡盲肠中活菌数减少，而接种柔嫩艾美耳球虫的鸡盲肠中活菌数逐渐增加。对盲肠内容物进行pH值、氧化还原电位以及短链脂肪酸和胆汁酸含量分析。在接种柔嫩艾美耳球虫的鸡盲肠中，氧化还原电位显著（P<0.05）向氧化阶段转变，挥发性脂肪酸（乙酸、丙酸和丁酸）浓度显著（P<0.05）降低。在需氧和厌氧培养中，体外活菌数随着脂肪酸摩尔浓度增加而减少。实验证据表明，接种柔嫩艾美耳球虫的鸡盲肠中鼠伤寒沙门氏菌的增殖与挥发性脂肪酸浓度降低有关。
